CPE

Gene Symbol CPE
Entrez Gene 280753
Alt Symbol CPH
Species Bovine
Gene Type protein-coding
Description carboxypeptidase E
Other Description carboxypeptidase H|enkephalin convertase|prohormone-processing carboxypeptidase
Swissprots A5PJN4 P04836 Q6YI55 Q52S88
Accessions DAA20941 P04836 AJ695849 BC142181 AAI42182 CB437028 CN434124 CO878372 DV829793 DV831465 EE221590 EE241409 EH201801 EW682509 X04411 CAA27999 XM_010813641 XP_010811943 NM_173903 NP_776328
Function Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing.
Subcellular Location Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions. {ECO:0000250}.
Top Pathways Type I diabetes mellitus

Anti-Carboxypeptidase H antibody - ab11044 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab11044 staining Carboxypeptidase H in murine pancreatic tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Tissue was fixed with paraformaldehyde and a heat mediated antigen retrieval step was performed using 10mM citrate buffer pH 6.0. Samples were then blocked with 5% serum for 1 hour at 20°C followed by incubation with the primary antibody at a 1/800 dilution for 16 hours at 4°C. A Cy2®-conjugated donkey anti-rabbit polyclonal was used as secondary antibody at a 1/200 dilution.See Abreview

Anti-Carboxypeptidase H antibody - ab11053 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Carboxypeptidase H antibody - ab84631 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pineal tissue labelling Carboxypeptidase H with ab84631 at 1/100. A Cy3-conjugated donkey anti-rabbit IgG (1/200) was used as the secondary antibody. Positive staining shown in the cytoplasm of cell bodies and processes of pinealocytes. Magnification: 20X. Exposure time: 0.5 - 2.0 seconds. Left - DAPI. Middle - Carboxypeptidase H. Right - Merge.
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