Gene Symbol |
CPE
|
Entrez Gene |
280753
|
Alt Symbol |
CPH
|
Species |
Bovine
|
Gene Type |
protein-coding
|
Description |
carboxypeptidase E
|
Other Description |
carboxypeptidase H|enkephalin convertase|prohormone-processing carboxypeptidase
|
Swissprots |
A5PJN4 P04836 Q6YI55 Q52S88
|
Accessions |
DAA20941 P04836 AJ695849 BC142181 AAI42182 CB437028 CN434124 CO878372 DV829793 DV831465 EE221590 EE241409 EH201801 EW682509 X04411 CAA27999 XM_010813641 XP_010811943 NM_173903 NP_776328
|
Function |
Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing.
|
Subcellular Location |
Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Secreted {ECO:0000250}. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions. {ECO:0000250}.
|
Top Pathways |
Type I diabetes mellitus
|