Gene Symbol | EIF4G3 |
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Entrez Gene | 8672 |
Alt Symbol | eIF-4G 3, eIF4G 3, eIF4GII |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic translation initiation factor 4 gamma, 3 |
Other Description | eIF-4-gamma 3|eIF-4-gamma II|eukaryotic translation initiation factor 4 gamma 3 |
Swissprots | Q5SWC3 Q8NEN1 O43432 Q504Z1 Q15597 B9EGQ7 |
Accessions | CBX47578 EAW94954 EAW94955 EAW94956 O43432 AB209119 BAD92356 AF012072 AAC02903 AK225489 AK294883 BAG57978 AK302087 BAG63474 AK302873 BAG64053 AK310195 BC030578 AAH30578 BC072413 BC094683 AAH94683 BC136643 AAI36644 BC144335 BE159364 BF084093 CN402454 DB042721 DB096818 Z34918 CAA84397 XM_011542356 XP_011540658 XM_011542357 XP_011540659 XM_011542358 XP_011540660 XM_011542359 XP_011540661 XM_011542360 XP_011540662 XM_011542361 XP_011540663 XM_011542362 XP_011540664 XM_011542363 XP_011540665 XM_011542364 XP_011540666 XM_011542365 XP_011540667 XM_011542366 XP_011540668 XM_011542367 XP_011540669 XM_011542368 XP_011540670 XM_011542369 XP_011540671 XM_011542370 XP_011540672 XM_011542371 XP_011540673 XM_011542372 XP_011540674 XM_011542373 XP_011540675 XM_011542374 XP_011540676 XM_011542375 XP_011540677 XM_011542376 XP_011540678 XM_011542377 XP_011540679 XM_011542378 XP_011540680 XM_011542379 XP_011540681 XM_011542380 XP_011540682 XM_011542381 XP_011540683 XM_011542382 XP_011540684 XR_946787 XR_946788 XR_946789 NM_001198801 NP_001185730 NM_001198802 NP_001185731 NM_001198803 NP_001185732 NM_003760 NP_003751 |
Function | Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1. {ECO:0000269|PubMed:9418880}. |
Top Pathways | RNA transport |
eIF4GII CRISPR/Cas9 KO Plasmid (h) - sc-416428 from Santa Cruz Biotechnology
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eIF4GII HDR Plasmid (h) - sc-416428-HDR from Santa Cruz Biotechnology
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eIF4GII Double Nickase Plasmid (h) - sc-416428-NIC from Santa Cruz Biotechnology
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eIF4GII Double Nickase Plasmid (h2) - sc-416428-NIC-2 from Santa Cruz Biotechnology
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eIF4GII CRISPR Activation Plasmid (h) - sc-416428-ACT from Santa Cruz Biotechnology
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eIF4GII CRISPR Activation Plasmid (h2) - sc-416428-ACT-2 from Santa Cruz Biotechnology
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eIF4GII Lentiviral Activation Particles (h) - sc-416428-LAC from Santa Cruz Biotechnology
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eIF4GII Lentiviral Activation Particles (h2) - sc-416428-LAC-2 from Santa Cruz Biotechnology
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eIF4GII siRNA (h) - sc-40558 from Santa Cruz Biotechnology
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eIF4GII shRNA Plasmid (h) - sc-40558-SH from Santa Cruz Biotechnology
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eIF4GII shRNA (h) Lentiviral Particles - sc-40558-V from Santa Cruz Biotechnology
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eIF4GII RNAi - H00008672-R01V from Novus Biologicals
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eIF4GII RNAi - H00008672-R01 from Novus Biologicals
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MISSION® esiRNA - EHU074971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7785 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7785 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06545 from Sigma-Aldrich
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EIF4G3 siRNA (Human) - CRH5706 from Cohesion Biosciences
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EIF4G3 - MBS827508 from MyBioSource
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shRNA set against Human EIF4G3 (NM_003760.4) - SHH284753 from Creative biogene
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Human EIF4G3 siRNA - orb266208 from Biorbyt
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EIF4G3 shRNA Plasmid (Human) - CHH5706 from Cohesion Biosciences
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EIF4G3 miRNA 3'UTR clone - MiUTR3H-06392 from Creative biogene
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