Gene Symbol | WRB |
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Entrez Gene | 7485 |
Alt Symbol | CHD5 |
Species | Human |
Gene Type | protein-coding |
Description | tryptophan rich basic protein |
Other Description | congenital heart disease 5 protein|tail-anchored protein insertion receptor WRB|tryptophan-rich basic protein|tryptophan-rich protein |
Swissprots | O60740 O00258 A8MQ44 A8KAP8 D3DSH9 |
Accessions | CAB90454 EAX09645 EAX09646 EAX09647 EAX09648 EAX09649 O00258 AK293113 BAF85802 AK293866 BAH11617 AK297186 BAG59675 AK299144 BAG61196 AK299245 BAG61276 AK310268 AW001614 BC012415 AAH12415 BC111393 AAI11394 DB498697 DB500750 Y12478 CAA73081 XM_005261059 XP_005261116 XM_005261060 XP_005261117 XM_005261061 XP_005261118 XM_011529744 XP_011528046 XM_011529745 XP_011528047 NM_001146218 NP_001139690 NM_004627 NP_004618 |
Function | Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane. {ECO:0000269|PubMed:21444755}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:21444755, ECO:0000269|PubMed:9544840}; Multi- pass membrane protein {ECO:0000269|PubMed:21444755, ECO:0000269|PubMed:9544840}. |
WRB CRISPR/Cas9 KO Plasmid (h) - sc-408383 from Santa Cruz Biotechnology
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WRB HDR Plasmid (h) - sc-408383-HDR from Santa Cruz Biotechnology
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WRB Double Nickase Plasmid (h) - sc-408383-NIC from Santa Cruz Biotechnology
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WRB Double Nickase Plasmid (h2) - sc-408383-NIC-2 from Santa Cruz Biotechnology
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WRB CRISPR Activation Plasmid (h) - sc-408383-ACT from Santa Cruz Biotechnology
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WRB CRISPR Activation Plasmid (h2) - sc-408383-ACT-2 from Santa Cruz Biotechnology
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WRB Lentiviral Activation Particles (h) - sc-408383-LAC from Santa Cruz Biotechnology
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WRB Lentiviral Activation Particles (h2) - sc-408383-LAC-2 from Santa Cruz Biotechnology
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WRB siRNA (h) - sc-91393 from Santa Cruz Biotechnology
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WRB shRNA Plasmid (h) - sc-91393-SH from Santa Cruz Biotechnology
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WRB shRNA (h) Lentiviral Particles - sc-91393-V from Santa Cruz Biotechnology
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Tryptophan rich protein RNAi - H00007485-R01 from Novus Biologicals
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CHD5 RNAi - H00026038-R02 from Novus Biologicals
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MISSION® esiRNA - EHU122161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22930 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22930 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06301 from Sigma-Aldrich
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WRB siRNA (Human) - CRH5124 from Cohesion Biosciences
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WRB - MBS8221211 from MyBioSource
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shRNA set against Human WRB (NM_004627.4) - SHH447440 from Creative biogene
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Human WRB siRNA - orb265626 from Biorbyt
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WRB shRNA Plasmid (Human) - CHH5124 from Cohesion Biosciences
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WRB miRNA 3'UTR clone - MiUTR3H-05408 from Creative biogene
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WRB miRNA 3'UTR clone - MiUTR3H-05409 from Creative biogene
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