| Gene Symbol |
REM1
|
| Entrez Gene |
28954
|
| Alt Symbol |
GD:REM, GES
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAS (RAD and GEM)-like GTP-binding 1
|
| Other Description |
GTP-binding protein REM 1|GTPase-regulating endothelial cell sprouting
|
| Swissprots |
E1P5L1 Q5TZR7 O75628 Q9NP57 Q5TZR8
|
| Accessions |
EAW76439 EAW76440 EAW76441 EAW76442 O75628 AF084465 AAC33132 AF152863 AAF74212 AK313060 BAG35890 BC039813 AAH39813 BT020078 AAV38881 BT020079 AAV38882 XM_005260404 XP_005260461 XM_011528795 XP_011527097 NM_014012 NP_054731
|
| Function |
Promotes endothelial cell sprouting and actin cytoskeletal reorganization. May be involved in angiogenesis. May function in Ca(2+) signaling.
|
| Tissue Specificity |
Most highly expressed in the endothelial lining of the blood vessels in uterus and heart. Lower levels found in spleen, lymph node, kidney and testis. Also found in cells with secretory function such as the islets of Langerhans, lobule/duct epithelium in the breast, bile duct epithelium in the liver, surface epithelium in the endometrial glands of the uterus, colon mucosa and acinar cells in the pancreas and the prostate.
|