Gene Symbol | MEPCE |
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Entrez Gene | 56257 |
Alt Symbol | BCDIN3 |
Species | Human |
Gene Type | protein-coding |
Description | methylphosphate capping enzyme |
Other Description | 7SK snRNA methylphosphate capping enzyme|bicoid-interacting protein 3 homolog|bin3 homolog|bin3, bicoid-interacting 3, homolog |
Swissprots | D6W5V7 Q9NPD4 B3KP86 Q7L2J0 |
Accessions | AAF74767 EAL23834 EAW76534 EAW76535 EAW76536 EAW76537 Q7L2J0 AI432993 AK000264 BAA91040 AK055964 BAG51598 AK291366 BAF84055 BC000556 AAH00556 BC016396 AAH16396 BC018935 AAH18935 BP217791 CB152355 CD672398 XM_011516410 XP_011514712 NM_001194990 NP_001181919 NM_001194991 NP_001181920 NM_001194992 NP_001181921 NM_019606 NP_062552 |
Function | S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it. {ECO:0000269|PubMed:17643375}. |
Tissue Specificity | Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. Weakly or not expressed in other tissues. {ECO:0000269|PubMed:12358911}. |
BCDIN3 CRISPR/Cas9 KO Plasmid (h) - sc-408262 from Santa Cruz Biotechnology
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BCDIN3 HDR Plasmid (h) - sc-408262-HDR from Santa Cruz Biotechnology
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BCDIN3 Double Nickase Plasmid (h) - sc-408262-NIC from Santa Cruz Biotechnology
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BCDIN3 Double Nickase Plasmid (h2) - sc-408262-NIC-2 from Santa Cruz Biotechnology
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BCDIN3 CRISPR Activation Plasmid (h) - sc-408262-ACT from Santa Cruz Biotechnology
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BCDIN3 CRISPR Activation Plasmid (h2) - sc-408262-ACT-2 from Santa Cruz Biotechnology
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BCDIN3 Lentiviral Activation Particles (h) - sc-408262-LAC from Santa Cruz Biotechnology
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BCDIN3 Lentiviral Activation Particles (h2) - sc-408262-LAC-2 from Santa Cruz Biotechnology
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BCDIN3 siRNA (h) - sc-72627 from Santa Cruz Biotechnology
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BCDIN3 shRNA Plasmid (h) - sc-72627-SH from Santa Cruz Biotechnology
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BCDIN3 shRNA (h) Lentiviral Particles - sc-72627-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU084711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13208 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13208 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04592 from Sigma-Aldrich
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MEPCE siRNA (Human) - CRJ1120 from Cohesion Biosciences
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shRNA set against Human MEPCE (NM_019606.5) - SHH340451 from Creative biogene
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Human MEPCE siRNA - orb271621 from Biorbyt
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MEPCE shRNA Plasmid (Human) - CHJ1120 from Cohesion Biosciences
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MEPCE miRNA 3'UTR clone - MiUTR3H-11921 from Creative biogene
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