Gene Symbol | CDC25A |
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Entrez Gene | 993 |
Alt Symbol | CDC25A2 |
Species | Human |
Gene Type | protein-coding |
Description | cell division cycle 25A |
Other Description | CDC25 isoform A1-CAG|CDC25A2-CAG isoform|M-phase inducer phosphatase 1|dual specificity phosphatase CDC25A |
Swissprots | P30304 Q8IZH5 Q9H2F2 Q96IL3 |
Accessions | AAM77917 AAY85387 EAW64849 EAW64850 EAW64851 EAW64852 P30304 AF277722 AAG41884 AI917350 AK290554 BAF83243 AY137580 AAN11305 BC007401 AAH07401 BC018642 AAH18642 BQ065803 BX392016 DQ890753 ABM81679 DQ892919 ABM83845 DQ896168 ABM87167 EU812118 ACI43572 FJ866789 ACZ05628 M81933 AAA58415 XM_006713434 XP_006713497 XM_006713435 XP_006713498 XM_006713436 XP_006713499 XM_011534316 XP_011532618 NM_001789 NP_001780 NM_201567 NP_963861 |
Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro. |
Top Pathways | Cell cycle, Progesterone-mediated oocyte maturation, MicroRNAs in cancer |
Cdc25A CRISPR/Cas9 KO Plasmid (h) - sc-400345 from Santa Cruz Biotechnology
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Cdc25A HDR Plasmid (h) - sc-400345-HDR from Santa Cruz Biotechnology
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Cdc25A Double Nickase Plasmid (h) - sc-400345-NIC from Santa Cruz Biotechnology
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Cdc25A Double Nickase Plasmid (h2) - sc-400345-NIC-2 from Santa Cruz Biotechnology
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Cdc25A CRISPR Activation Plasmid (h) - sc-400345-ACT from Santa Cruz Biotechnology
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Cdc25A CRISPR Activation Plasmid (h2) - sc-400345-ACT-2 from Santa Cruz Biotechnology
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Cdc25A Lentiviral Activation Particles (h) - sc-400345-LAC from Santa Cruz Biotechnology
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Cdc25A Lentiviral Activation Particles (h2) - sc-400345-LAC-2 from Santa Cruz Biotechnology
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Cdc25A siRNA (h) - sc-29254 from Santa Cruz Biotechnology
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Cdc25A shRNA Plasmid (h) - sc-29254-SH from Santa Cruz Biotechnology
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Cdc25A shRNA (h) Lentiviral Particles - sc-29254-V from Santa Cruz Biotechnology
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CDC25A RNAi - H00000993-R02 from Novus Biologicals
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MISSION® esiRNA - EHU063231 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0057 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0056 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0055 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2017 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2017 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13186 from Sigma-Aldrich
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CDC25A siRNA (Human) - CRH0707 from Cohesion Biosciences
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CDC25A RNAi - H00000993-R01 from Novus Biologicals
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CDC25A - MBS8201906 from MyBioSource
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shRNA set against Human CDC25A (NM_001789.2) - SHH259681 from Creative biogene
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shRNA set against Human CDC25A(NM_001789.2) - SHG160523 from Creative biogene
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shRNA set against Human CDC25A(NM_201567.1) - SHG160541 from Creative biogene
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