| Gene Symbol | Acsl1 |
|---|---|
| Entrez Gene | 14081 |
| Alt Symbol | Acas, Acas1, Acs, FACS, Facl2, LACS 1, LACS1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | acyl-CoA synthetase long-chain family member 1 |
| Other Description | acetate-CoA ligase|acetyl-CoA synthetase|acetyl-Coenzyme A synthetase 1 (ADP forming)|fatty acid Coenzyme A ligase, long chain 2|long-chain acyl-CoA synthetase 1|long-chain-fatty-acid--CoA ligase 1 |
| Swissprots | Q6GTG6 Q9DBK5 P41216 |
| Accessions | CBF65114 CBU89985 EDL35573 EDL35574 P41216 AK004897 BAB23652 AK145900 BAE26736 AK149406 BAE28854 AK152772 BAE31484 AK153050 BAE31678 AK158388 AK161189 BAE36230 AK168078 BAE40051 AK180785 AK216738 AK216933 BC006692 BC056644 AAH56644 BY094311 BY142492 BY393025 BY786934 U15977 AAA52193 XM_006509262 XP_006509325 XM_006509264 XP_006509327 XM_006509265 XP_006509328 XM_006509266 XP_006509329 NM_001302163 NP_001289092 NM_007981 NP_032007 |
| Function | Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses oleate, arachidonate, eicosapentaenoate and docosahexaenoate as substrates (By similarity). {ECO:0000250}. |
| Subcellular Location | Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. |
| Top Pathways | Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation |