Gene Symbol | LTA4H |
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Entrez Gene | 4048 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | leukotriene A4 hydrolase |
Other Description | LTA-4 hydrolase|leukotriene A-4 hydrolase |
Swissprots | B4DNQ9 F8VV40 Q6IAT6 P09960 Q9UCT7 |
Accessions | AAA89077 AAC24315 EAW97557 EAW97558 EAW97559 EAW97560 P09960 AB209740 BAD92977 AK293630 BAG57086 AK298017 BAG60321 AK301308 BAG62860 AK308184 AK310461 AK310522 BC032528 AAH32528 BC036555 AAH36555 BX647158 CR457068 CAG33349 DB019628 DC358373 J02959 AAA36177 J03459 AAA36176 JF432734 ADZ15951 R41544 XM_005268871 XP_005268928 XM_011538348 XP_011536650 XM_011538349 XP_011536651 NM_000895 NP_000886 NM_001256643 NP_001243572 NM_001256644 NP_001243573 |
Function | Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. {ECO:0000269|PubMed:11917124, ECO:0000269|PubMed:12207002, ECO:0000269|PubMed:15078870, ECO:0000269|PubMed:18804029, ECO:0000269|PubMed:1897988, ECO:0000269|PubMed:1975494, ECO:0000269|PubMed:2244921}. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Isoform 1 and isoform 2 are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. |
Top Pathways | Arachidonic acid metabolism |
Active human Leukotriene A4 hydrolase full length protein - ab174008 from Abcam
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Human Leukotriene A4 hydrolase full length protein - ab152506 from Abcam
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Human Leukotriene A4 hydrolase full length protein - ab198440 from Abcam
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Human Leukotriene A4 hydrolase full length protein - ab201716 from Abcam
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LTA4H / LTA4 Antibody Blocking Peptide - LS-E19561 from LifeSpan Bioscience
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LTA4H / LTA4 Antibody Blocking Peptide - LS-E19562 from LifeSpan Bioscience
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LTA4H / LTA4 Antibody Blocking Peptide - LS-E7146 from LifeSpan Bioscience
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Leukotriene A4 Hydrolase/LTA4H Recombinant Protein - H00004048-P01 from Novus Biologicals
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LTA4H-Antibody-Center-Blocking-Peptide - BP2844c from Abgent, a WuXi AppTec company
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Recombinant Human Leukotriene A4 Hydrolase/LTA4H, CF - 4008-ZN-010 from R&D Systems
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LTA4H Blocking Peptide - 33R-6634 from Fitzgerald
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LTA4H Blocking Peptide - 33R-4201 from Fitzgerald
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LTA4H protein - 80R-4209 from Fitzgerald
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LTA4H (1-611, His-tag) - AR51891PU-N from Acris Antibodies
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LTA4H (1-611, His-tag) - AR51891PU-S from Acris Antibodies
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LTA4H - H00004048-P01-10 from Acris Antibodies
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LTA4H - H00004048-P01-25 from Acris Antibodies
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Leukotriene A4 Hydrolase Recombinant Protein - 96-524 from ProSci
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LTA4H fusion protein - ag4568 from Proteintech Group
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Recombinant Human LTA4H, His tagged - LTA4H-305H from Creative Biomart
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Recombinant Human LTA4H, His-tagged - LTA4H-51H from Creative Biomart
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Recombinant Leukotriene A4 Hydrolase (LTA4H) - RPD236Hu01 from Uscn Life Science Inc.
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Recombinant Leukotriene A4 Hydrolase (LTA4H) - RPD236Mu01 from Uscn Life Science Inc.
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Recombinant Leukotriene A4 Hydrolase (LTA4H) - RPD236Mu02 from Uscn Life Science Inc.
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Human LTA4H Protein - LTH-H5220 from ACROBiosystems
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