Gene Symbol | HP |
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Entrez Gene | 100008816 |
Alt Symbol | - |
Species | Rabbit |
Gene Type | protein-coding |
Description | haptoglobin |
Other Description | zonulin |
Swissprots | Q8MKG3 P19007 Q9MYU3 |
Accessions | P19007 AF372520 AAM21313 AJ250102 CAB96389 NM_001082110 NP_001075579 |
Function | As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Anti -Haptoglobin (Zonulin, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP) - 140579 from USBiological Life Science
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Anti -Haptoglobin (Zonulin, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP) (AP) - 140579-AP from USBiological Life Science
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Anti -Haptoglobin (Zonulin, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP) (APC) - 140579-APC from USBiological Life Science
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Anti -Haptoglobin (Zonulin, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP) (Biotin) - 140579-Biotin from USBiological Life Science
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Anti -Haptoglobin (Zonulin, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP) (FITC) - 140579-FITC from USBiological Life Science
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Anti -Haptoglobin (Zonulin, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP) (HRP) - 140579-HRP from USBiological Life Science
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Anti -Haptoglobin (Zonulin, Haptoglobin alpha Chain, Haptoglobin beta Chain, HP) (PE) - 140579-PE from USBiological Life Science
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Haptoglobin Antibody - abx100573 from Abbexa
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Haptoglobin Antibody - abx112923 from Abbexa
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Anti-Haptoglobin (Hpt) - 20-3230 from ARP American Research Products
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HP Antibody - CSB-PA010691GA01HU from Cusabio
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Polyclonal Antibody to Haptoglobin (Hpt) - PAA817Rb51 from Cloud-clone
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Polyclonal Antibody to Haptoglobin (Hpt) - PAA817Rb52 from Cloud-clone
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Polyclonal Antibody to Haptoglobin (Hpt) - PAA817Rb53 from Cloud-clone
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Biotin-Linked Antibody to Haptoglobin (Hpt) - PAA817Rb71 from Cloud-clone
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Haptoglobin, Polyclonal Antibody - MBS2027587 from MyBioSource
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Haptoglobin, Polyclonal Antibody - MBS2026578 from MyBioSource
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Haptoglobin, Polyclonal Antibody - MBS2027117 from MyBioSource
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Haptoglobin, Polyclonal Antibody - MBS2028228 from MyBioSource
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Haptoglobin, Polyclonal Antibody - MBS2026232 from MyBioSource
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Haptoglobin, Polyclonal Antibody - MBS2027002 from MyBioSource
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Haptoglobin (Hpt) Polyclonal Antibody - CAU27051 from Biomatik
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