Gene Symbol | PRSS12 |
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Entrez Gene | 8492 |
Alt Symbol | BSSP-3, BSSP3, MRT1 |
Species | Human |
Gene Type | protein-coding |
Description | protease, serine, 12 (neurotrypsin, motopsin) |
Other Description | brain-specific serine protease 3|leydin|neurotrypsin |
Swissprots | P56730 Q9UP16 |
Accessions | CAB69270 EAX06317 EAX06318 P56730 AF077298 AAD25919 AJ001531 CAA04816 BC007761 AAH07761 BG386264 XM_005263318 XP_005263375 XM_011532387 XP_011530689 NM_003619 NP_003610 |
Function | Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Brain and Leydig cells of the testis. |
Neurotrypsin CRISPR/Cas9 KO Plasmid (h) - sc-411180 from Santa Cruz Biotechnology
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Neurotrypsin HDR Plasmid (h) - sc-411180-HDR from Santa Cruz Biotechnology
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Neurotrypsin Double Nickase Plasmid (h) - sc-411180-NIC from Santa Cruz Biotechnology
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Neurotrypsin Double Nickase Plasmid (h2) - sc-411180-NIC-2 from Santa Cruz Biotechnology
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Neurotrypsin CRISPR Activation Plasmid (h) - sc-411180-ACT from Santa Cruz Biotechnology
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Neurotrypsin CRISPR Activation Plasmid (h2) - sc-411180-ACT-2 from Santa Cruz Biotechnology
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Neurotrypsin Lentiviral Activation Particles (h) - sc-411180-LAC from Santa Cruz Biotechnology
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Neurotrypsin Lentiviral Activation Particles (h2) - sc-411180-LAC-2 from Santa Cruz Biotechnology
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Neurotrypsin siRNA (h) - sc-88946 from Santa Cruz Biotechnology
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Neurotrypsin shRNA Plasmid (h) - sc-88946-SH from Santa Cruz Biotechnology
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Neurotrypsin shRNA (h) Lentiviral Particles - sc-88946-V from Santa Cruz Biotechnology
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Neurotrypsin RNAi - H00008492-R01 from Novus Biologicals
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MISSION® esiRNA - EHU129801 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2166 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2166 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05798 from Sigma-Aldrich
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PRSS12 siRNA (Human) - CRH5567 from Cohesion Biosciences
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shRNA set against Human PRSS12 (NM_003619.3) - SHH384340 from Creative biogene
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PRSS12 shRNA Plasmid (Human) - CHH5567 from Cohesion Biosciences
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PRSS12 miRNA 3'UTR clone - MiUTR3H-08668 from Creative biogene
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