Gene Symbol | IAPP |
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Entrez Gene | 3375 |
Alt Symbol | DAP, IAP |
Species | Human |
Gene Type | protein-coding |
Description | islet amyloid polypeptide |
Other Description | Islet amyloid polypeptide (diabetes-associated peptide; amylin)|amylin|diabetes-associated peptide|insulinoma amyloid peptide |
Swissprots | P10997 Q14598 Q0ZD87 |
Accessions | AAA35524 AAA35983 AAA51728 CAA33031 CAA37002 CAA39504 CAA48724 CAB57803 CAB57804 EAW96426 EAW96427 P10997 BC111849 AAI11850 BQ548699 CK905016 DQ516082 ABG27010 J04422 AAA52281 X14904 CAA33032 X14905 CAA33033 NM_000415 NP_000406 |
Function | Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. |
Subcellular Location | Secreted {ECO:0000269|PubMed:17374526}. |
Top Pathways | Maturity onset diabetes of the young |
Amylin CRISPR/Cas9 KO Plasmid (h) - sc-416691 from Santa Cruz Biotechnology
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Amylin HDR Plasmid (h) - sc-416691-HDR from Santa Cruz Biotechnology
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Amylin Double Nickase Plasmid (h) - sc-416691-NIC from Santa Cruz Biotechnology
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Amylin Double Nickase Plasmid (h2) - sc-416691-NIC-2 from Santa Cruz Biotechnology
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Amylin CRISPR Activation Plasmid (h) - sc-416691-ACT from Santa Cruz Biotechnology
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Amylin CRISPR Activation Plasmid (h2) - sc-416691-ACT-2 from Santa Cruz Biotechnology
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Amylin Lentiviral Activation Particles (h) - sc-416691-LAC from Santa Cruz Biotechnology
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Amylin Lentiviral Activation Particles (h2) - sc-416691-LAC-2 from Santa Cruz Biotechnology
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Amylin siRNA (h) - sc-39275 from Santa Cruz Biotechnology
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Amylin shRNA Plasmid (h) - sc-39275-SH from Santa Cruz Biotechnology
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Amylin shRNA (h) Lentiviral Particles - sc-39275-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10421 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08257 from Sigma-Aldrich
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IAPP siRNA (Human) - CRH2297 from Cohesion Biosciences
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IAPP - MBS8230655 from MyBioSource
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shRNA set against Human IAP (NM_000415.2) - SHH316281 from Creative biogene
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IAPP shRNA Plasmid (Human) - CHH2297 from Cohesion Biosciences
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IAPP miRNA 3'UTR clone - MiUTR4H-TG04380 from Creative biogene
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