Gene Symbol | ATXN3L |
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Entrez Gene | 92552 |
Alt Symbol | MJDL |
Species | Human |
Gene Type | protein-coding |
Description | ataxin 3-like |
Other Description | machado-Joseph disease protein 1-like|putative ataxin-3-like protein |
Swissprots | Q9H3M9 B2RNY8 |
Accessions | EAW98819 Q9H3M9 AB050195 BAB18799 AK302365 BAG63689 BC137186 AAI37187 BC137187 AAI37188 DB059638 DB460385 DB525796 DB540973 NM_001135995 NP_001129467 |
Function | Deubiquitinating enzyme that cleaves both 'Lys-48'- linked and 'Lys-63'-linked poly-ubiquitin chains (in vitro). |
Subcellular Location | Nucleus {ECO:0000250}. |
Top Pathways | Protein processing in endoplasmic reticulum |
ATXN3L CRISPR/Cas9 KO Plasmid (h) - sc-409001 from Santa Cruz Biotechnology
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ATXN3L HDR Plasmid (h) - sc-409001-HDR from Santa Cruz Biotechnology
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ATXN3L Double Nickase Plasmid (h) - sc-409001-NIC from Santa Cruz Biotechnology
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ATXN3L Double Nickase Plasmid (h2) - sc-409001-NIC-2 from Santa Cruz Biotechnology
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ATXN3L CRISPR Activation Plasmid (h) - sc-409001-ACT from Santa Cruz Biotechnology
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ATXN3L CRISPR Activation Plasmid (h2) - sc-409001-ACT-2 from Santa Cruz Biotechnology
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ATXN3L Lentiviral Activation Particles (h) - sc-409001-LAC from Santa Cruz Biotechnology
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ATXN3L Lentiviral Activation Particles (h2) - sc-409001-LAC-2 from Santa Cruz Biotechnology
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ATXN3L siRNA (h) - sc-105111 from Santa Cruz Biotechnology
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ATXN3L shRNA Plasmid (h) - sc-105111-SH from Santa Cruz Biotechnology
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ATXN3L shRNA (h) Lentiviral Particles - sc-105111-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU117471 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3763 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3763 from Sigma-Aldrich
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ATXN3L siRNA (Human) - CRJ4145 from Cohesion Biosciences
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ATXN3L - MBS8225224 from MyBioSource
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shRNA set against Human ATXN3L (NM_001135995.1) - SHH243594 from Creative biogene
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ATXN3L shRNA Plasmid (Human) - CHJ4145 from Cohesion Biosciences
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ATXN3L miRNA 3'UTR clone - MiUTR3H-13702 from Creative biogene
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