| Gene Symbol |
MUCL1
|
| Entrez Gene |
118430
|
| Alt Symbol |
SBEM
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
mucin-like 1
|
| Other Description |
mucin-like protein 1|small breast epithelial mucin
|
| Swissprots |
Q0VG95 Q96DR8 Q32ZB5
|
| Accessions |
CAM55960 EAW96795 Q96DR8 AF414087 AAL02119 AI905624 AY359062 AAQ89421 AY651259 AAT72303 BC111421 AAI11422 XM_011537868 XP_011536170 NM_058173 NP_477521
|
| Function |
May play a role as marker for the diagnosis of metastatic breast cancer. {ECO:0000269|PubMed:12019145, ECO:0000269|PubMed:12595743, ECO:0000269|PubMed:15684711}.
|
| Subcellular Location |
Secreted {ECO:0000305|PubMed:15880534}. Membrane {ECO:0000305|PubMed:15880534}.
|
| Tissue Specificity |
Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic cells. {ECO:0000269|PubMed:12019145, ECO:0000269|PubMed:12595743, ECO:0000269|PubMed:15096563}.
|
![Western Blot: SBEM Overexpression Lysate (Adult Normal) [NBL1-13393] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SBEM.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7813_SBEM%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13393-img0002.jpg)