| Gene Symbol |
JMJD1C
|
| Entrez Gene |
221037
|
| Alt Symbol |
TRIP8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
jumonji domain containing 1C
|
| Other Description |
TR-interacting protein 8|TRIP-8|jumonji domain-containing protein 1C|probable JmjC domain-containing histone demethylation protein 2C|thyroid hormone receptor interactor 8|thyroid receptor interacting protein 8|thyroid receptor-interacting protein 8
|
| Swissprots |
Q7Z3E7 Q9P2G7 Q5SR00 A0T124 Q96KB9 Q5SQZ9 Q15652 Q5SQZ8 Q8N3U0
|
| Accessions |
CBX47531 CBX47532 EAW54242 EAW54243 Q15652 AB037801 BAA92618 AK024991 AK027280 AK056660 AK095584 AK123507 AK126040 AL831917 CAD38578 AU185724 BC026268 AAH26268 BC037981 BC047331 BC065742 BC067238 BC108649 BC126403 BC143722 AAI43723 BC156414 AAI56415 BF243713 BX537954 CAD97921 DR002533 DR762886 EF068222 ABK64187 L40411 AAC41741 XM_005269624 XP_005269681 XM_005269626 XP_005269683 XM_011539502 XP_011537804 XM_011539503 XP_011537805 XM_011539504 XP_011537806 XM_011539505 XP_011537807 XM_011539506 XP_011537808 XM_011539507 XP_011537809 XM_011539508 XP_011537810 XR_945628 XR_945629 NM_004241 NM_001282948 NP_001269877 NM_032776 NP_116165
|
| Function |
Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}.
|
| Top Pathways |
Transcriptional misregulation in cancer
|