Gene Symbol | LCN1 |
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Entrez Gene | 3933 |
Alt Symbol | PMFA, TLC, TP, VEGP |
Species | Human |
Gene Type | protein-coding |
Description | lipocalin 1 |
Other Description | VEG protein|Von Ebner gland protein|lipocalin 1 (tear prealbumin)|lipocalin-1|protein migrating faster than albumin|tear prealbumin |
Swissprots | P31025 Q5T8A1 |
Accessions | AAA18633 EAW88156 EAW88157 P31025 BC065721 AAH65721 BC074925 AAH74925 BC074926 AAH74926 CD721968 CK429694 CK430667 CK431106 M90424 AAA61845 X62418 CAA44284 X67647 CAA47889 XM_011518675 XP_011516977 NM_001252617 NP_001239546 NM_001252618 NP_001239547 NM_001252619 NP_001239548 NM_002297 NP_002288 |
Function | Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket. |
Subcellular Location | Secreted. |
Tissue Specificity | Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate. |
Lipocalin-1 CRISPR/Cas9 KO Plasmid (h) - sc-416763 from Santa Cruz Biotechnology
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Lipocalin-1 HDR Plasmid (h) - sc-416763-HDR from Santa Cruz Biotechnology
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Lipocalin-1 Double Nickase Plasmid (h) - sc-416763-NIC from Santa Cruz Biotechnology
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Lipocalin-1 Double Nickase Plasmid (h2) - sc-416763-NIC-2 from Santa Cruz Biotechnology
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Lipocalin-1 CRISPR Activation Plasmid (h) - sc-416763-ACT from Santa Cruz Biotechnology
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Lipocalin-1 CRISPR Activation Plasmid (h2) - sc-416763-ACT-2 from Santa Cruz Biotechnology
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Lipocalin-1 Lentiviral Activation Particles (h) - sc-416763-LAC from Santa Cruz Biotechnology
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Lipocalin-1 Lentiviral Activation Particles (h2) - sc-416763-LAC-2 from Santa Cruz Biotechnology
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Lipocalin-1 siRNA (h) - sc-45477 from Santa Cruz Biotechnology
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Lipocalin-1 shRNA Plasmid (h) - sc-45477-SH from Santa Cruz Biotechnology
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Lipocalin-1 shRNA (h) Lentiviral Particles - sc-45477-V from Santa Cruz Biotechnology
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Lipocalin-1 RNAi - H00003933-R01 from Novus Biologicals
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MISSION® esiRNA - EHU112561 from Sigma-Aldrich
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MISSION® esiRNA - EHU110191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11601 from Sigma-Aldrich
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LCN1 siRNA (Human) - CRH2665 from Cohesion Biosciences
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shRNA set against Human LCN1 (NM_002297.3) - SHH329023 from Creative biogene
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LCN1 shRNA Plasmid (Human) - CHH2665 from Cohesion Biosciences
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LCN1 miRNA 3'UTR clone - MiUTR4H-TG05004 from Creative biogene
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