| Gene Symbol |
TSTD1
|
| Entrez Gene |
100131187
|
| Alt Symbol |
KAT
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
|
| Other Description |
putative thiosulfate sulfurtransferase KAT|thiosulfate sulfurtransferase KAT, putative|thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1
|
| Swissprots |
Q5SY50 Q5SY49 Q9BV22 Q5SY51 Q8NFU3 Q8NFU2 Q5SY48
|
| Accessions |
AAM69839 AAM69840 EAW52679 Q8NFU3 AV688621 BC001699 AAH01699 BC038219 CD675389 NM_001113205 NP_001106676 NM_001113206 NP_001106677 NM_001113207 NP_001106678
|
| Function |
Possible role in tumorigenesis.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000269|PubMed:12817473}. Note=Localized around the nuclear membranes.
|
| Tissue Specificity |
Highly expressed in kidney, liver and skeletal muscle. Lower levels of expression in heart, colon, thymus, spleen, placenta and lung. Weakly expressed in brain, small intestine and peripheral blood leukocytes. Expressed at high levels in the breast carcinoma cell lines MCF-7 and MDA-MB-468 and at a lower level in the breast carcinoma cell line MDA-MB-231, the colon carcinoma call line LoVo and the lung carcinoma cell line A- 549. No expression in the cell lines EFO-27 and HeLa, or the normal breast tissue cell lines MCF-10A and H184A1. Detected in invasive ductal carcinoma, but not in the adjacent tissues. {ECO:0000269|PubMed:12817473}.
|
![Western Blot: TSTD1 Antibody [NBP1-81566] - Analysis in human cell line SK-BR-3.](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_8/24863_TSTD1-Antibody-Western-Blot-NBP1-81566-img0005.jpg)
![Immunocytochemistry/Immunofluorescence: TSTD1 Antibody [NBP2-58888] - Staining of human cell line HEK 293 shows localization to cytosol & cytoplasmic bodies.](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_10/1188_TSTD1%2520Antibody-Immunocytochemistry-Immunofluorescence-NBP2-58888-img0001.jpg)