| Gene Symbol |
WNT4
|
| Entrez Gene |
54361
|
| Alt Symbol |
SERKAL, WNT-4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
wingless-type MMTV integration site family, member 4
|
| Other Description |
protein Wnt-4
|
| Swissprots |
Q9H1J8 Q9UJM2 Q9BXF5 Q5TZQ0 B4DJF9 Q96T81 P56705
|
| Accessions |
AAK25765 CAI38644 EAW95010 P56705 AA984007 AB061675 BAC23080 AF086347 AF316543 AAK51699 AK296058 BAG58821 AY009398 AAG38658 AY358947 AAQ89306 BC007386 BC057781 AAH57781 BT020125 AAV38928 JF432754 ADZ15971 XM_011541597 XP_011539899 XM_011541598 XP_011539900 XM_011541599 XP_011539901 NM_030761 NP_110388
|
| Function |
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). Overexpression may be associated with abnormal proliferation in human breast tissue. {ECO:0000250}.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
| Top Pathways |
HTLV-I infection, Proteoglycans in cancer, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, Wnt signaling pathway
|
![Western Blot: WNT4 Overexpression Lysate (Adult Normal) [NBL1-17871] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for WNT4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7606_WNT4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17871-img0002.jpg)