Gene Symbol | GHRHR |
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Entrez Gene | 2692 |
Alt Symbol | GHRFR, GRFR, IGHD1B |
Species | Human |
Gene Type | protein-coding |
Description | growth hormone releasing hormone receptor |
Other Description | GHRH receptor|GRF receptor|growth hormone-releasing hormone receptor |
Swissprots | Q02643 Q99863 |
Accessions | AAB18630 AAB18631 AAB18632 AAB37758 AAC23789 BAC05924 EAL24445 EAW93973 EAW93974 EAW93975 EAW93976 EAW93977 Q02643 AB058895 BAB40232 AF282259 AAG15368 AF282260 AAG15369 AF282261 AAG15370 AF282262 AAG15371 AV750179 AY557192 AAS59864 BC166636 AAI66636 DB348314 L01406 AAA35890 L09237 AAA58619 S79912 AAD14318 XM_011515263 XP_011513565 NM_000823 NP_000814 NM_001009824 |
Function | Receptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Pituitary gland. |
Top Pathways | Neuroactive ligand-receptor interaction |
GHRH-R CRISPR/Cas9 KO Plasmid (h) - sc-404197 from Santa Cruz Biotechnology
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GHRH-R HDR Plasmid (h) - sc-404197-HDR from Santa Cruz Biotechnology
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GHRH-R Double Nickase Plasmid (h) - sc-404197-NIC from Santa Cruz Biotechnology
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GHRH-R Double Nickase Plasmid (h2) - sc-404197-NIC-2 from Santa Cruz Biotechnology
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GHRH-R CRISPR Activation Plasmid (h) - sc-404197-ACT from Santa Cruz Biotechnology
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GHRH-R CRISPR Activation Plasmid (h2) - sc-404197-ACT-2 from Santa Cruz Biotechnology
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GHRH-R Lentiviral Activation Particles (h) - sc-404197-LAC from Santa Cruz Biotechnology
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GHRH-R Lentiviral Activation Particles (h2) - sc-404197-LAC-2 from Santa Cruz Biotechnology
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GHRH-R siRNA (h) - sc-72353 from Santa Cruz Biotechnology
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GHRH-R shRNA Plasmid (h) - sc-72353-SH from Santa Cruz Biotechnology
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GHRH-R shRNA (h) Lentiviral Particles - sc-72353-V from Santa Cruz Biotechnology
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GHRHR RNAi - H00002692-R04 from Novus Biologicals
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GHRHR RNAi - H00002692-R03 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9277 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9277 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01639 from Sigma-Aldrich
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GHRHR siRNA (Human) - CRH1795 from Cohesion Biosciences
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GHRHR - MBS8213630 from MyBioSource
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shRNA set against Human Ghrhr (NM_000823.3) - SHH300982 from Creative biogene
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GHRHR shRNA Plasmid (Human) - CHH1795 from Cohesion Biosciences
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