HMGB1

Gene Symbol	HMGB1
Entrez Gene	3146
Alt Symbol	HMG1, HMG3, SBP-1
Species	Human
Gene Type	protein-coding
Description	high mobility group box 1
Other Description	Amphoterin|HMG-1|Sulfoglucuronyl carbohydrate binding protein|high mobility group protein 1|high mobility group protein B1|high-mobility group (nonhistone chromosomal) protein 1|high-mobility group box 1
Swissprots	Q14321 A5D8W9 P09429 Q6IBE1 Q5T7C3
Accessions	AAB08987 AAF71287 AAK64599 ABM47301 ABS29271 EAX08457 EAX08458 EAX08459 EAX08460 EAX08461 EAX08462 P09429 AA430980 AB208998 BAD92235 AF401215 AK057120 BAG51867 AK122825 BAG53745 AK291494 BAF84183 AK304506 BAH14201 AK310975 AL110194 AX795278 CAE48262 AY377859 AAQ91389 BC003378 AAH03378 BC030981 AAH30981 BC066889 AAH66889 BC067732 AAH67732 BC140013 AAI40014 BC140018 AAI40019 BC141844 AAI41845 BT006940 AAP35586 BT020159 AAV38961 BX647267 CR456863 CAG33144 CR749614 CAH18408 D63874 BAA09924 L13804 L13805 X12597 CAA31110 XM_005266363 XP_005266420 XM_005266365 XP_005266422 XM_005266368 XP_005266425 XM_011535055 XP_011533357 XM_011535056 XP_011533358 XR_941568 NM_002128 NP_002119
Function	DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus. Chromosome.
Top Pathways	Base excision repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

HMGB1-Over-expression-Lysate - LY12677a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

HMGB1 HEK293 Cell Transient Overexpression Lysate (Non-Denatured) - L128T6 from Acris Antibodies Category Cell Lysate Prices $290.00 Sizes 100 µg

HMGB1 293 Cell Lysate - 400744 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

HMGB1/HMG-1 Overexpression Lysate (Native) - NBL1-11614 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

HMG-1 (h): 293 Lysate - sc-110487 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

HMGB1 Over-expression Lysate Product - GWB-CC709A from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Human HMGB1 / HMG1 HEK293 Cell Lysate (WB positive control) - 10326-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human HMGB1 / HMG1 HEK293 Cell Lysate (WB positive control) - 10326-H01HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human HMGB1 Human Cells Transfected Lysate (positive control) (denatured) - orb173674 from Biorbyt Category Cell Lysate Prices $425.00 Sizes 300 μg Species Human

Human HMGB1 Human Cells Transfected Lysate (positive control) (denatured) - orb172918 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human HMGB1 Knockdown Stable Cell Line - CSC-DC007116 from Creative biogene Category Cell Line Species Human

HMGB1 Knockout Cell Line-HeLa - CSC-RT1762 from Creative biogene Category Cell Line Species Human

HMGB1 KO Cell Lysate-HeLa - CLKO-1608 from Creative biogene Category Cell Lysate

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