Gene Symbol |
EBAG9
|
Entrez Gene |
9166
|
Alt Symbol |
EB9, PDAF
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
estrogen receptor binding site associated, antigen, 9
|
Other Description |
cancer-associated surface antigen RCAS1|estrogen receptor-binding fragment-associated gene 9 protein|receptor-binding cancer antigen expressed on SiSo cells
|
Swissprots |
Q9BS76 Q5Y8C7 A8K3N6 Q6IB20 O00559
|
Accessions |
EAW91932 EAW91933 EAW91934 O00559 AA812215 AB007619 BAA22572 AF006265 AAB61617 AI619447 AK290651 BAF83340 AK308950 AL515533 AY515724 AAR97974 AY653072 AAU85838 BC005249 AAH05249 BC017729 AAH17729 BC022506 AAH22506 BG427211 BG616704 BG707115 BI194881 CA450508 CD108096 CR456984 CAG33265 DQ891464 ABM82390 DQ894642 ABM85568 NM_001278938 NP_001265867 NM_004215 NP_004206 NM_198120 NP_936056
|
Function |
May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1- beta converting enzyme (ICE)-like proteases. {ECO:0000269|PubMed:12054692, ECO:0000269|PubMed:12138241, ECO:0000269|PubMed:12672804}.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:12672804}; Single-pass type III membrane protein {ECO:0000269|PubMed:12672804}. Note=According to PubMed:10426319, it also exists as a soluble form which has the same biological activities. The existence of such soluble form is however uncertain.
|
Tissue Specificity |
Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs.
|