Gene Symbol | SECTM1 |
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Entrez Gene | 6398 |
Alt Symbol | K12 |
Species | Human |
Gene Type | protein-coding |
Description | secreted and transmembrane 1 |
Other Description | secreted and transmembrane protein 1|type 1a transmembrane protein |
Swissprots | B2R7H0 O00466 Q8WVN6 |
Accessions | CAC22100 EAW89766 Q8WVN6 AK223068 BAD96788 AK223104 BAD96824 AK290708 BAF83397 AK312980 BAG35817 BC017716 AAH17716 BI861812 DA589733 EU831815 ACE87333 EU831892 ACE86651 JF432651 ADZ15868 U77643 AAC52044 XM_005256392 XP_005256449 XM_011523588 XP_011521890 NM_003004 NP_002995 |
Function | May be involved in thymocyte signaling. {ECO:0000269|PubMed:15742156}. |
Subcellular Location | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Secreted. |
Tissue Specificity | Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts. {ECO:0000269|PubMed:15742156, ECO:0000269|PubMed:9480746}. |
K12 CRISPR/Cas9 KO Plasmid (h) - sc-408689 from Santa Cruz Biotechnology
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K12 HDR Plasmid (h) - sc-408689-HDR from Santa Cruz Biotechnology
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K12 Double Nickase Plasmid (h) - sc-408689-NIC from Santa Cruz Biotechnology
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K12 Double Nickase Plasmid (h2) - sc-408689-NIC-2 from Santa Cruz Biotechnology
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K12 CRISPR Activation Plasmid (h) - sc-408689-ACT from Santa Cruz Biotechnology
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K12 CRISPR Activation Plasmid (h2) - sc-408689-ACT-2 from Santa Cruz Biotechnology
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K12 Lentiviral Activation Particles (h) - sc-408689-LAC from Santa Cruz Biotechnology
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K12 Lentiviral Activation Particles (h2) - sc-408689-LAC-2 from Santa Cruz Biotechnology
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K12 siRNA (h) - sc-93717 from Santa Cruz Biotechnology
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K12 shRNA Plasmid (h) - sc-93717-SH from Santa Cruz Biotechnology
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K12 shRNA (h) Lentiviral Particles - sc-93717-V from Santa Cruz Biotechnology
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SECTM1 RNAi - H00006398-R01 from Novus Biologicals
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MISSION® esiRNA - EHU018821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19047 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19047 from Sigma-Aldrich
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SECTM1 siRNA (Human) - CRH4320 from Cohesion Biosciences
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SECTM1 - MBS8209757 from MyBioSource
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shRNA set against Human SECTM1 (NM_003004.2) - SHH403980 from Creative biogene
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shRNA set against Human SECTM1(NM_003004.2) - SHR212550 from Creative biogene
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SECTM1 shRNA Plasmid (Human) - CHH4320 from Cohesion Biosciences
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SECTM1 miRNA 3'UTR clone - MiUTR1H-09237 from Creative biogene
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