Gene Symbol | HRH1 |
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Entrez Gene | 3269 |
Alt Symbol | H1-R, H1R, HH1R, hisH1 |
Species | Human |
Gene Type | protein-coding |
Description | histamine receptor H1 |
Other Description | histamine H1 receptor|histamine receptor, subclass H1 |
Swissprots | Q6P9E5 A8K047 P35367 |
Accessions | AAD14833 BAA03319 BAA94465 CAA04289 CAA54182 EAW64092 P35367 AF026261 AAB95156 AK289412 BAF82101 AK292157 BAF84846 AK312879 BAG35729 AY136743 AAN01269 BC060802 AAH60802 BM905371 BP366267 D28481 BAA05840 DA372691 DB073635 DC300229 Z34897 CAA84380 XM_011533652 XP_011531954 XM_011533653 XP_011531955 XM_011533654 XP_011531956 XM_011533655 XP_011531957 NM_000861 NP_000852 NM_001098211 NP_001091681 NM_001098212 NP_001091682 NM_001098213 NP_001091683 |
Function | In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21697825}; Multi-pass membrane protein {ECO:0000269|PubMed:21697825}. |
Top Pathways | Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction |
Human Histamine H1 R (AAH60802) VersaClone cDNA - RDC0341 from R&D Systems
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Mouse Histamine H1 R (NP_032311) VersaClone cDNA - RDC0392 from R&D Systems
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Human HRH1 cDNA clone(NM_001098212.1) - CDFH008774 from Creative Biomart
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Human HRH1 cDNA clone(NM_001098211.1) - CDFH008775 from Creative Biomart
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Human HRH1 cDNA clone(NM_001098213.1) - CDFH008776 from Creative Biomart
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Human HRH1 ORF Clone(NM_000861.3) - CDCL166482 from Creative Biomart
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Human HRH1 ORF Clone(NM_001098211.1) - CDCR346446 from Creative Biomart
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Human HRH1 ORF Clone(NM_001098211.1) - CDCR346447 from Creative Biomart
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Human HRH1 ORF Clone(NM_001098212.1) - CDCR346448 from Creative Biomart
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Human HRH1 ORF Clone(NM_001098212.1) - CDCR346449 from Creative Biomart
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Human HRH1 ORF Clone(NM_001098213.1) - CDCR346450 from Creative Biomart
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Human HRH1 ORF Clone(NM_001098213.1) - CDCR346451 from Creative Biomart
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Human HRH1 ORF Clone(NM_001098211.1) - CDCR346446 from Creative biogene
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Human HRH1 ORF Clone(NM_001098212.1) - CDCR346448 from Creative biogene
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Human HRH1 ORF Clone(NM_001098213.1) - CDCR346450 from Creative biogene
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Human HRH1 cDNA Clone(NM_001098212.1) - CDFH008774 from Creative biogene
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Human HRH1 cDNA Clone(NM_001098211.1) - CDFH008775 from Creative biogene
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Human HRH1 cDNA Clone(NM_001098213.1) - CDFH008776 from Creative biogene
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