Gene Symbol | CP |
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Entrez Gene | 1356 |
Alt Symbol | CP-2 |
Species | Human |
Gene Type | protein-coding |
Description | ceruloplasmin (ferroxidase) |
Other Description | ceruloplasmin |
Swissprots | Q14063 P00450 Q9UKS4 Q2PP18 |
Accessions | AAB33996 AAF02483 ABC40726 ACB21047 BAA08084 BAA08085 EAW78882 EAW78883 EAW78884 P00450 AK095290 BAG53020 AK291219 BAF83908 AK299272 BAH12988 AK309279 BC039239 BC061702 BC070304 AAH70304 BC094709 BC142714 AAI42715 BC146663 AAI46664 BC146801 BX647327 CA391602 CB321657 D00025 BAA00019 DC334592 M13536 AAA51975 M13699 AAA51976 X04135 CAA27752 X04136 CAA27753 X04137 CAA27754 X04138 CAA27755 X69706 XM_006713499 XP_006713562 XM_006713500 XP_006713563 XM_006713501 XP_006713564 XM_006713502 XP_006713565 XM_011512435 XP_011510737 XR_427361 NM_000096 NP_000087 NR_046371 |
Function | Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. Note=Colocalizes with GCP1 in secretory intracellular compartments. {ECO:0000250}. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Top Pathways | Porphyrin and chlorophyll metabolism |
Human Ceruloplasmin full length protein - ab77930 from Abcam
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Human Ceruloplasmin full length protein - ab168882 from Abcam
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Human Ceruloplasmin peptide - ab111803 from Abcam
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Mouse Ceruloplasmin full length protein - ab167767 from Abcam
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Rat Ceruloplasmin full length protein - ab168722 from Abcam
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CP / Ceruloplasmin Antibody Blocking Peptide - LS-E8877 from LifeSpan Bioscience
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CP / Ceruloplasmin Antibody Blocking Peptide - LS-E8878 from LifeSpan Bioscience
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Ceruloplasmin Native Protein - NBP2-12553 from Novus Biologicals
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Ceruloplasmin Human Expressed Protein - P4942 from Novus Biologicals
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CP-Antibody-Center-Blocking-Peptide - BP7340c from Abgent, a WuXi AppTec company
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CP-Antibody-N-term-Blocking-Peptide - BP7340a from Abgent, a WuXi AppTec company
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Recombinant human Ceruloplasmin (OPCA01042) - OPCA01042 from Aviva Systems Biology
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Human Plasma Ceruloplasmin Protein (OPMA04248) - OPMA04248 from Aviva Systems Biology
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Ceruloplasmin protein - orb170097 from Biorbyt
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Human Plasma Ceruloplasmin protein - orb82123 from Biorbyt
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Human CP protein - orb245598 from Biorbyt
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Ceruloplasmin protein - orb170098 from Biorbyt
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Ceruloplasmin protein - 30C-CP1010 from Fitzgerald
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Human Ceruloplasmin Protein - abx065855 from Abbexa
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Ceruloplasmin - BA120 from Acris Antibodies
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Ceruloplasmin - P4942 from Acris Antibodies
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Human Plasma Ceruloplasmin - MD-14-0027P from RayBiotech
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Ceruloplasmin - 13-3019 from ARP American Research Products
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Ceruloplasmin (CP), Human - 20-7313 from ARP American Research Products
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CP fusion protein - ag15535 from Proteintech Group
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