Gene Symbol | PRKRIR |
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Entrez Gene | 5612 |
Alt Symbol | DAP4, P52rIPK, THAP0, THAP12 |
Species | Human |
Gene Type | protein-coding |
Description | protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) |
Other Description | 52 kDa repressor of the inhibitor of the protein kinase|58 kDa interferon-induced protein kinase-interacting protein|THAP domain containing 12|THAP domain-containing protein 0|death-associated protein 4|inhibitor of protein kinase PKR|p58IPK-interacting protein |
Swissprots | Q9Y3Z4 Q8WTW1 Q17RY9 A8K728 O43422 |
Accessions | EAW74991 EAW74992 EAW74993 O43422 AA765102 AF007393 AAC39564 AF081567 AAG01570 AK001522 AK291843 BAF84532 AK299594 BAG61526 AL049970 CAB43226 BC021992 AAH21992 BC110304 AAI10305 BC117138 AAI17139 BC117140 AAI17141 BX641144 DR005363 HQ258648 ADR83399 NM_004705 NP_004696 NR_130898 |
Function | Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR- inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth. |
DAP-4 CRISPR/Cas9 KO Plasmid (h) - sc-410955 from Santa Cruz Biotechnology
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DAP-4 HDR Plasmid (h) - sc-410955-HDR from Santa Cruz Biotechnology
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DAP-4 Double Nickase Plasmid (h) - sc-410955-NIC from Santa Cruz Biotechnology
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DAP-4 Double Nickase Plasmid (h2) - sc-410955-NIC-2 from Santa Cruz Biotechnology
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DAP-4 CRISPR Activation Plasmid (h) - sc-410955-ACT from Santa Cruz Biotechnology
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DAP-4 CRISPR Activation Plasmid (h2) - sc-410955-ACT-2 from Santa Cruz Biotechnology
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DAP-4 Lentiviral Activation Particles (h) - sc-410955-LAC from Santa Cruz Biotechnology
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DAP-4 Lentiviral Activation Particles (h2) - sc-410955-LAC-2 from Santa Cruz Biotechnology
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DAP-4 siRNA (h) - sc-77093 from Santa Cruz Biotechnology
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DAP-4 shRNA Plasmid (h) - sc-77093-SH from Santa Cruz Biotechnology
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DAP-4 shRNA (h) Lentiviral Particles - sc-77093-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU109331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17431 from Sigma-Aldrich
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PRKRIR siRNA (Human) - CRH3782 from Cohesion Biosciences
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PRKRIR RNAi - H00005612-R01 from Novus Biologicals
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shRNA set against Human PRKRIR (NM_004705.2) - SHH383008 from Creative biogene
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shRNA set against Human PRKRIR(NM_004705.2) - SHR141006 from Creative biogene
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Human PRKRIR siRNA - orb264284 from Biorbyt
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PRKRIR shRNA Plasmid (Human) - CHH3782 from Cohesion Biosciences
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PRKRIR miRNA 3'UTR clone - MiUTR1H-08291 from Creative biogene
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