| Gene Symbol |
KLRF1
|
| Entrez Gene |
51348
|
| Alt Symbol |
CLEC5C, NKp80
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
killer cell lectin-like receptor subfamily F, member 1
|
| Other Description |
C-type lectin domain family 5 member C|activating coreceptor NKp80|killer cell lectin-like receptor F1|killer cell lectin-like receptor subfamily F member 1|lectin-like receptor F1
|
| Swissprots |
Q96PR2 Q9NZS1 Q9NZS2 Q4KMT5 Q96PR3
|
| Accessions |
EAW96124 EAW96125 EAW96126 Q9NZS2 AF175206 AAF37804 AF175207 AAF37805 AF267244 AAL14873 AF267245 AAL14874 AJ305370 CAC29425 BC096734 AAH96734 BC098166 AAH98166 BC098257 AAH98257 BC098354 AAH98354 XR_931301 XR_931302 XR_931303 NM_001291822 NP_001278751 NM_001291823 NP_001278752 NM_016523 NP_057607 NR_120305
|
| Function |
Involved in the natural killer (NK)-mediated cytolysis of PHA-induced lymphoblasts.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Strongly expressed in peripheral blood leukocytes and spleen, with weaker expression in lymph node and adult liver, and no expression detected in bone marrow, thymus, and fetal liver. Not expressed in brain, heart, placenta, lung, kidney, skeletal muscle, and pancreas. Within peripheral blood leukocyte and immunocyte cell lines, expression was predominant in NK cells but was also detected in monocytes. {ECO:0000269|PubMed:10671213}.
|
![Western Blot: KLRF1 Overexpression Lysate (Adult Normal) [NBL1-12366] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for KLRF1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9481_KLRF1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-12366-img0002.jpg)