| Gene Symbol |
Ggt5
|
| Entrez Gene |
29566
|
| Alt Symbol |
Ggta1, Ggtla1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
gamma-glutamyltransferase 5
|
| Other Description |
GGL|GGT 5|GGT-rel|gamma-glutamyl leukotrienase|gamma-glutamyl transpeptidase-related enzyme|gamma-glutamyltransferase-like activity 1|gamma-glutamyltranspeptidase 5|glutathione hydrolase 5|leukotriene-C4 hydrolase
|
| Swissprots |
Q9QWE9
|
| Accessions |
EDL97198 Q9QWE9 BC087018 AAH87018 U76252 AAC23546 NM_019235 NP_062108
|
| Function |
Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4).
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea.
|
| Top Pathways |
Taurine and hypotaurine metabolism, Glutathione metabolism, Arachidonic acid metabolism, Cyanoamino acid metabolism
|