| Gene Symbol | Ggt5 |
|---|---|
| Entrez Gene | 29566 |
| Alt Symbol | Ggta1, Ggtla1 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | gamma-glutamyltransferase 5 |
| Other Description | GGL|GGT 5|GGT-rel|gamma-glutamyl leukotrienase|gamma-glutamyl transpeptidase-related enzyme|gamma-glutamyltransferase-like activity 1|gamma-glutamyltranspeptidase 5|glutathione hydrolase 5|leukotriene-C4 hydrolase |
| Swissprots | Q9QWE9 |
| Accessions | EDL97198 Q9QWE9 BC087018 AAH87018 U76252 AAC23546 NM_019235 NP_062108 |
| Function | Cleaves the gamma-glutamyl peptide bond of glutathione conjugates, but maybe not glutathione itself. Converts leukotriene C4 (LTC4) to leukotriene D4 (LTD4). |
| Subcellular Location | Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Tissue Specificity | Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea. |
| Top Pathways | Taurine and hypotaurine metabolism, Glutathione metabolism, Arachidonic acid metabolism, Cyanoamino acid metabolism |