Gene Symbol | GZF1 |
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Entrez Gene | 64412 |
Alt Symbol | ZBTB23, ZNF336 |
Species | Human |
Gene Type | protein-coding |
Description | GDNF-inducible zinc finger protein 1 |
Other Description | zinc finger and BTB domain-containing protein 23|zinc finger protein 336 |
Swissprots | Q96N08 A8K199 Q9H116 Q54A22 D3DW39 B4DF58 Q9H6W6 B3KPL4 Q9BQK9 B2RBC3 Q9H117 |
Accessions | EAX10159 EAX10160 EAX10161 Q9H116 AA062926 AB100265 BAC98464 AK025447 BAB15134 AK056159 BAB71107 AK056477 BAG51726 AK289814 BAF82503 AK293942 BAG57319 AK295362 BAG58326 AK314599 BAG37170 BC016049 BC125188 BC154409 BE348947 BM975844 XM_005260797 XP_005260854 XM_005260800 XP_005260857 XM_005260801 XP_005260858 XM_005260802 XP_005260859 XM_005260803 XP_005260860 XM_006723607 XP_006723670 XM_011529321 XP_011527623 XM_011529322 XP_011527624 NM_022482 NP_071927 |
Function | Transcriptional repressor. Binds the GZF1 responsive element (GRE) (consensus: 5'-TGCGCN[TG][CA]TATA-3'). May be regulating VSX2/HOX10 expression. {ECO:0000269|PubMed:14522971, ECO:0000269|PubMed:16049025}. |
Subcellular Location | Nucleus, nucleoplasm. Nucleus, nucleolus. Note=Nuclear localization depends upon NCL. |
Tissue Specificity | Expressed in adult brain, heart, skeletal muscle, kidney and liver. Also detected in fetal brain and kidney, and at lower levels in fetal lung and liver. {ECO:0000269|PubMed:14522971}. |
ZNF336 CRISPR/Cas9 KO Plasmid (h) - sc-409496 from Santa Cruz Biotechnology
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ZNF336 HDR Plasmid (h) - sc-409496-HDR from Santa Cruz Biotechnology
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ZNF336 Double Nickase Plasmid (h) - sc-409496-NIC from Santa Cruz Biotechnology
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ZNF336 Double Nickase Plasmid (h2) - sc-409496-NIC-2 from Santa Cruz Biotechnology
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ZNF336 CRISPR Activation Plasmid (h) - sc-409496-ACT from Santa Cruz Biotechnology
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ZNF336 CRISPR Activation Plasmid (h2) - sc-409496-ACT-2 from Santa Cruz Biotechnology
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ZNF336 Lentiviral Activation Particles (h) - sc-409496-LAC from Santa Cruz Biotechnology
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ZNF336 Lentiviral Activation Particles (h2) - sc-409496-LAC-2 from Santa Cruz Biotechnology
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ZNF336 siRNA (h) - sc-76979 from Santa Cruz Biotechnology
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ZNF336 shRNA Plasmid (h) - sc-76979-SH from Santa Cruz Biotechnology
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ZNF336 shRNA (h) Lentiviral Particles - sc-76979-V from Santa Cruz Biotechnology
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ZNF336 RNAi - H00064412-R01 from Novus Biologicals
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MISSION® esiRNA - EHU087681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9825 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9825 from Sigma-Aldrich
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GZF1 siRNA (Human) - CRJ2012 from Cohesion Biosciences
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GZF1 - MBS8210304 from MyBioSource
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shRNA set against Human Gzf1 (NM_022482.3) - SHH309626 from Creative biogene
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GZF1 shRNA Plasmid (Human) - CHJ2012 from Cohesion Biosciences
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GZF1 miRNA 3'UTR clone - MiUTR1H-04342 from Creative biogene
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