SUMF2
| Gene Symbol | SUMF2 |
|---|---|
| Entrez Gene | 25870 |
| Alt Symbol | pFGE |
| Species | Human |
| Gene Type | protein-coding |
| Description | sulfatase modifying factor 2 |
| Other Description | C-alpha-formyglycine-generating enzyme 2|C-alpha-formylglycine-generating enzyme 2|paralog of the formylglycine-generating enzyme|sulfatase-modifying factor 2 |
| Swissprots | Q96BH2 Q14DW5 B4DWQ0 Q8NBJ7 Q53ZE3 B4DU41 Q9Y405 Q9BRN3 Q9BWI1 |
| Accessions | AAS07452 CAI72149 EAX07975 EAX07976 EAX07977 EAX07978 EAX07979 EAX07980 EAX07981 EAX07982 EAX07983 EAX07984 EAX07985 EAX07986 Q8NBJ7 AF075046 AK075477 BAC11643 AK297042 BAG59569 AK297793 BAG60133 AK298605 BAG60789 AK300488 BAG62203 AK301627 BAG63112 AL050037 CAB43247 AY323911 AAP86218 AY359103 AAQ89461 BC000224 AAH00224 BC006159 AAH06159 BC015600 AAH15600 BC065222 BC084539 AAH84539 BC111092 AAI11093 BM423367 BP256067 BP296294 CA439848 CF131206 CR936749 CR936757 CX164099 DA130450 DA917807 DA924174 DB010869 XM_011515254 XP_011513556 XM_011515255 XP_011513557 XR_246509 NM_001042469 NP_001035934 NM_001042470 NP_001035935 NM_001130069 NP_001123541 NM_001146333 NP_001139805 NM_015411 NP_056226 NM_001042468 NM_001130070 |
| Function | Lacks formyl-glycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1. {ECO:0000269|PubMed:12757706, ECO:0000269|PubMed:15708861, ECO:0000269|PubMed:15962010}. |
| Subcellular Location | Endoplasmic reticulum lumen {ECO:0000269|PubMed:15708861, ECO:0000269|PubMed:15962010}. |
| Tissue Specificity | Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta. {ECO:0000269|PubMed:15708861, ECO:0000269|PubMed:15962010}. |
SUMF2 CRISPR/Cas9 KO Plasmid (h) - sc-408847 from Santa Cruz Biotechnology
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SUMF2 HDR Plasmid (h) - sc-408847-HDR from Santa Cruz Biotechnology
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SUMF2 Double Nickase Plasmid (h) - sc-408847-NIC from Santa Cruz Biotechnology
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SUMF2 Double Nickase Plasmid (h2) - sc-408847-NIC-2 from Santa Cruz Biotechnology
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SUMF2 CRISPR Activation Plasmid (h) - sc-408847-ACT from Santa Cruz Biotechnology
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SUMF2 CRISPR Activation Plasmid (h2) - sc-408847-ACT-2 from Santa Cruz Biotechnology
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SUMF2 Lentiviral Activation Particles (h) - sc-408847-LAC from Santa Cruz Biotechnology
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SUMF2 Lentiviral Activation Particles (h2) - sc-408847-LAC-2 from Santa Cruz Biotechnology
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SUMF2 siRNA (h) - sc-89517 from Santa Cruz Biotechnology
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SUMF2 shRNA Plasmid (h) - sc-89517-SH from Santa Cruz Biotechnology
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SUMF2 shRNA (h) Lentiviral Particles - sc-89517-V from Santa Cruz Biotechnology
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Sulfatase Modifying Factor 2/SUMF2 RNAi - H00025870-R03 from Novus Biologicals
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Sulfatase Modifying Factor 2/SUMF2 RNAi - H00025870-R02 from Novus Biologicals
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Sulfatase Modifying Factor 2/SUMF2 RNAi - H00025870-R04 from Novus Biologicals
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Sulfatase Modifying Factor 2/SUMF2 RNAi - H00025870-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN20830 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20830 from Sigma-Aldrich
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SUMF2 siRNA (Human) - CRH8553 from Cohesion Biosciences
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SUMF2 - MBS8216032 from MyBioSource
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shRNA set against Human SUMF2 (NM_015411.2) - SHH420888 from Creative biogene
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shRNA set against Human SUMF2(NM_015411.2) - SHL047826 from Creative biogene
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shRNA set against Human SUMF2(NM_001042469.1) - SHL047880 from Creative biogene
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shRNA set against Human SUMF2(NM_001042470.1) - SHL047898 from Creative biogene
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Human SUMF2 siRNA - orb269055 from Biorbyt
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SUMF2 shRNA Plasmid (Human) - CHH8553 from Cohesion Biosciences
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