| Gene Symbol |
Amhr2
|
| Entrez Gene |
110542
|
| Alt Symbol |
Misiir, Misrii, Mrii
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
anti-Mullerian hormone type 2 receptor
|
| Other Description |
AMH type II receptor|MIS type II receptor|anti-Muellerian hormone type II receptor|anti-Muellerian hormone type-2 receptor|anti-Mullerian hormone type 2 receptor delta 2|anti-Mullerian hormone type 2 receptor delta 9/10
|
| Swissprots |
Q0VDQ4 Q8K592
|
| Accessions |
AAC64138 EDL03983 EDL03984 Q8K592 AF503863 AAM28608 BB052908 BB868995 BC119571 AAI19572 BC119572 CJ194934 KC920726 AGK89952 KC920727 AGK89953 XM_006520293 XP_006520356 XM_006520294 XP_006520357 NM_144547 NP_653130
|
| Function |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway
|