Robo1

Gene Symbol Robo1
Entrez Gene 58946
Alt Symbol -
Species Rat
Gene Type protein-coding
Description roundabout, axon guidance receptor, homolog 1 (Drosophila)
Other Description roundabout homolog 1
Swissprots O55005
Accessions O55005 AF041082 AAC39960 XM_008768533 XP_008766755 XM_008768534 XP_008766756 XM_008768535 XP_008766757 XM_008768536 XP_008766758 NM_022188 NP_071524
Function Receptor for SLIT1 and SLIT2 which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex. May be required for lung development (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Expressed in embryonal brain and spinal chord. {ECO:0000269|PubMed:10102268, ECO:0000269|PubMed:9458045}.
Top Pathways Axon guidance

ROBO1 Antibody - AF1749 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal
ROBO1 was detected in perfusion fixed frozen sections of rat brain using Goat Anti-Rat ROBO1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF1749) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling if primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

ROBO1 Antibody [Biotin] - BAF1749 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

ROBO1 - GT15144 from Neuromics

Prices $365.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Image: ROBO-1 staining of cryostat tissue sections of rat embryo (Neural Tube) at  a concentration of 5 µg/mL using HRP-DAB detection (brown) and counterstained with hematoxylin (blue).

Goat anti-Rat ROBO1 Polyclonal antibody, Biotin-Conjugated - DPABY-670 from Creative Diagnostics

Host Goat
Clonality Polyclonal
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