ATP5J2
| Gene Symbol | ATP5J2 |
|---|---|
| Entrez Gene | 9551 |
| Alt Symbol | ATP5JL |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 |
| Other Description | ATP synthase f chain, mitochondrial|ATP synthase subunit f, mitochondrial|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit f|F1F0-type ATPase subunit f|F1Fo-ATP synthase complex Fo membrane domain f subunit|F1Fo-ATPase synthase f subunit |
| Swissprots | C9J8H9 O76079 P56134 F8W7V3 Q6IBB3 Q96L83 Q9BTI8 |
| Accessions | CAI93419 EAL23877 EAW76661 P56134 AF047436 AAC39887 AF088918 AAC34895 AK094388 AK123419 AK223348 BAD97068 AY046911 AAL06647 BC003678 AAH03678 BE139254 BU587946 CB110074 CB155273 CD173604 CD176299 CN274665 CR456891 CAG33172 CR542155 CAG46952 DA064847 DB114195 EL952520 NM_001003713 NP_001003713 NM_001003714 NP_001003714 NM_001039178 NP_001034267 NM_004889 NP_004880 NM_001190353 NM_001190354 |
| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. |
| Subcellular Location | Mitochondrion. Mitochondrion inner membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Top Pathways | Oxidative phosphorylation |
ATP5J2 CRISPR/Cas9 KO Plasmid (h) - sc-417174 from Santa Cruz Biotechnology
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ATP5J2 HDR Plasmid (h) - sc-417174-HDR from Santa Cruz Biotechnology
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ATP5J2 Double Nickase Plasmid (h) - sc-417174-NIC from Santa Cruz Biotechnology
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ATP5J2 Double Nickase Plasmid (h2) - sc-417174-NIC-2 from Santa Cruz Biotechnology
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ATP5J2 CRISPR Activation Plasmid (h) - sc-417174-ACT from Santa Cruz Biotechnology
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ATP5J2 CRISPR Activation Plasmid (h2) - sc-417174-ACT-2 from Santa Cruz Biotechnology
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ATP5J2 Lentiviral Activation Particles (h) - sc-417174-LAC from Santa Cruz Biotechnology
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ATP5J2 Lentiviral Activation Particles (h2) - sc-417174-LAC-2 from Santa Cruz Biotechnology
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ATP5J2 siRNA (h) - sc-89543 from Santa Cruz Biotechnology
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ATP5J2 shRNA Plasmid (h) - sc-89543-SH from Santa Cruz Biotechnology
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ATP5J2 shRNA (h) Lentiviral Particles - sc-89543-V from Santa Cruz Biotechnology
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ATP5J2 RNAi - H00009551-R03 from Novus Biologicals
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ATP5J2 RNAi - H00009551-R01 from Novus Biologicals
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ATP5J2 RNAi - H00009551-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN3707 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3707 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01215 from Sigma-Aldrich
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ATP5J2 siRNA (Human) - CRH6352 from Cohesion Biosciences
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ATP5J2 - MBS8210976 from MyBioSource
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shRNA set against Human ATP5J2 (NM_004889.3) - SHH242874 from Creative biogene
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Human ATP5J2 siRNA - orb266854 from Biorbyt
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ATP5J2 shRNA Plasmid (Human) - CHH6352 from Cohesion Biosciences
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ATP5J2 miRNA 3'UTR clone - MiUTR3H-13687 from Creative biogene
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ATP5J2 miRNA 3'UTR clone - MiUTR3H-13688 from Creative biogene
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