Gene Symbol | AMD1 |
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Entrez Gene | 262 |
Alt Symbol | ADOMETDC, AMD, SAMDC |
Species | Human |
Gene Type | protein-coding |
Description | adenosylmethionine decarboxylase 1 |
Other Description | S-adenosylmethionine decarboxylase 1|S-adenosylmethionine decarboxylase proenzyme |
Swissprots | Q9BWK4 P17707 E1P5F7 Q5VXN6 Q5VXN4 |
Accessions | AAD14903 EAW48307 EAW48308 EAW48309 P17707 AA808049 AJ420527 AJ420567 AK026205 AK125644 AK130474 AK300330 BAG62078 AK302761 BAG63972 AK304351 BAG65194 AK316471 BAH14842 AL832698 CAI46113 AU134914 BC000171 AAH00171 BC041345 BX640599 CAE45705 DQ894110 ABM85036 M21154 AAA51716 NM_001287214 NP_001274143 NM_001287215 NP_001274144 NM_001287216 NP_001274145 NM_001634 NP_001625 NR_109768 NM_001033059 |
Function | Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels (By similarity). {ECO:0000250}. |
Top Pathways | Cysteine and methionine metabolism, Arginine and proline metabolism |
AdoMetDC CRISPR/Cas9 KO Plasmid (h) - sc-404514 from Santa Cruz Biotechnology
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AdoMetDC HDR Plasmid (h) - sc-404514-HDR from Santa Cruz Biotechnology
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AdoMetDC Double Nickase Plasmid (h) - sc-404514-NIC from Santa Cruz Biotechnology
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AdoMetDC Double Nickase Plasmid (h2) - sc-404514-NIC-2 from Santa Cruz Biotechnology
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AdoMetDC CRISPR Activation Plasmid (h) - sc-404514-ACT from Santa Cruz Biotechnology
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AdoMetDC CRISPR Activation Plasmid (h2) - sc-404514-ACT-2 from Santa Cruz Biotechnology
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AdoMetDC Lentiviral Activation Particles (h) - sc-404514-LAC from Santa Cruz Biotechnology
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AdoMetDC Lentiviral Activation Particles (h2) - sc-404514-LAC-2 from Santa Cruz Biotechnology
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AdoMetDC siRNA (h) - sc-95296 from Santa Cruz Biotechnology
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AdoMetDC shRNA Plasmid (h) - sc-95296-SH from Santa Cruz Biotechnology
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AdoMetDC shRNA (h) Lentiviral Particles - sc-95296-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU105741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3105 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3105 from Sigma-Aldrich
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AMD1 siRNA (Human) - CRH0179 from Cohesion Biosciences
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AMD1 - MBS8221092 from MyBioSource
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shRNA set against Human AMD1 (NM_001634.4) - SHH235670 from Creative biogene
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shRNA set against Human AMD1(NM_001634.4) - SHG055429 from Creative biogene
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shRNA set against Human AMD1(NM_001033059.1) - SHG055475 from Creative biogene
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AMD1 shRNA Plasmid (Human) - CHH0179 from Cohesion Biosciences
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AMD1 miRNA 3'UTR clone - MiUTR1H-00329 from Creative biogene
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AMD1 miRNA 3'UTR clone - MiUTR1H-00330 from Creative biogene
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