Gene Symbol | CYS1 |
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Entrez Gene | 192668 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cystin 1 |
Other Description | cilia-associated protein|cystin-1 |
Swissprots | Q717R9 |
Accessions | EAX00971 Q717R9 AF544983 AAQ11748 AK091299 AW298291 BC148588 AAI48589 BC156921 AAI56922 BE907159 DB559824 NM_001037160 NP_001032237 |
Subcellular Location | Cell projection, cilium membrane {ECO:0000269|PubMed:22085962}; Lipid-anchor {ECO:0000269|PubMed:22085962}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:22085962}. Note=Expression is enriched in the ciliary axoneme. Localization to cilium is mediated via interaction with UNC119 and UNC119B, which bind to the myristoyl moiety of the N-terminus. |
Tissue Specificity | Expressed at high levels in the kidney and pancreas. Moderate expression seen in the skeletal muscle, liver and heart. A weak expression seen in the brain, lung, uterus, prostate, testis, small intestine and colon. |
CYS1 CRISPR/Cas9 KO Plasmid (h) - sc-414949 from Santa Cruz Biotechnology
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CYS1 HDR Plasmid (h) - sc-414949-HDR from Santa Cruz Biotechnology
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CYS1 Double Nickase Plasmid (h) - sc-414949-NIC from Santa Cruz Biotechnology
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CYS1 Double Nickase Plasmid (h2) - sc-414949-NIC-2 from Santa Cruz Biotechnology
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CYS1 CRISPR Activation Plasmid (h) - sc-414949-ACT from Santa Cruz Biotechnology
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CYS1 CRISPR Activation Plasmid (h2) - sc-414949-ACT-2 from Santa Cruz Biotechnology
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CYS1 Lentiviral Activation Particles (h) - sc-414949-LAC from Santa Cruz Biotechnology
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CYS1 Lentiviral Activation Particles (h2) - sc-414949-LAC-2 from Santa Cruz Biotechnology
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CYS1 siRNA (h) - sc-94561 from Santa Cruz Biotechnology
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CYS1 shRNA Plasmid (h) - sc-94561-SH from Santa Cruz Biotechnology
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CYS1 shRNA (h) Lentiviral Particles - sc-94561-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU220391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6897 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6897 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00126 from Sigma-Aldrich
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CYS1 siRNA (Human) - CRJ6156 from Cohesion Biosciences
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CYS1 - MBS8228637 from MyBioSource
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shRNA set against Human CYS1 (NM_001037160.2) - SHH273865 from Creative biogene
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CYS1 shRNA Plasmid (Human) - CHJ6156 from Cohesion Biosciences
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