| Gene Symbol |
ARHGAP9
|
| Entrez Gene |
64333
|
| Alt Symbol |
10C, RGL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rho GTPase activating protein 9
|
| Other Description |
rho GTPase-activating protein 9|rho-type GTPase-activating protein 9
|
| Swissprots |
Q8TCJ3 Q96EZ2 Q8NAF3 Q8WYR0 B4DVI3 Q96S74 E9PDX9 Q9BRR9
|
| Accessions |
EAW97014 EAW97015 EAW97016 EAW97017 EAW97018 Q9BRR9 AB030239 BAB83128 AB051853 BAB56159 AF161339 AAF28899 AK057573 BAG51936 AK092763 BAC03969 AK131415 BAD18562 AK300910 BAG62545 AK301095 BAG62695 AK304107 BAG65010 AL713803 CAD28552 BC006107 AAH06107 BC011820 AAH11820 CB528354 DA675251 DQ896430 ABM87429 EU176437 ABW03888 XM_005269082 XP_005269139 XM_005269083 XP_005269140 XM_005269084 XP_005269141 XM_005269085 XP_005269142 XM_006719560 XP_006719623 XM_011538656 XP_011536958 XM_011538657 XP_011536959 XM_011538658 XP_011536960 XM_011538659 XP_011536961 XM_011538660 XP_011536962 XM_011538661 XP_011536963 XM_011538662 XP_011536964 XM_011538663 XP_011536965 NM_001080156 NP_001073625 NM_001080157 NP_001073626 NM_032496 NP_115885
|
| Function |
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has a substantial GAP activity toward CDC42 and RAC1 and less toward RHOA. Has a role in regulating adhesion of hematopoietic cells to the extracellular matrix. Binds phosphoinositides, and has the highest affinity for phosphatidylinositol 3,4,5-trisphosphate, followed by phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate. {ECO:0000269|PubMed:11396949}.
|
| Tissue Specificity |
Predominantly expressed in peripheral blood leukocytes, spleen, and thymus. {ECO:0000269|PubMed:11396949}.
|
