Gene Symbol | SPECC1L |
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Entrez Gene | 23384 |
Alt Symbol | CYTSA, GBBB2, OBLFC1 |
Species | Human |
Gene Type | protein-coding |
Description | sperm antigen with calponin homology and coiled-coil domains 1-like |
Other Description | SPECC1-like protein|cytokinesis and spindle organization A|cytospin-A|renal carcinoma antigen NY-REN-22 |
Swissprots | F5H1H6 Q69YQ0 B7Z758 O15081 |
Accessions | EAW59656 EAW59657 Q69YQ0 AA773104 AB002374 BAA21574 AK025531 AK097129 AK301482 BAH13494 AL832425 CAH10609 AY884293 AAX84184 BC005093 BC013085 BC021132 BC041571 BC068611 BC136471 AAI36472 BM126792 BM556934 BM720120 BQ929263 CN334545 DA385554 HY105216 NM_001145468 NP_001138940 NM_001254732 NP_001241661 NM_001254733 NP_001241662 NM_015330 NP_056145 |
Function | Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration. {ECO:0000269|PubMed:21703590}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:21703590}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:21703590}. Cell junction, gap junction {ECO:0000269|PubMed:21703590}. Note=Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center. |
Cytospin-A CRISPR/Cas9 KO Plasmid (h) - sc-406628 from Santa Cruz Biotechnology
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Cytospin-A HDR Plasmid (h) - sc-406628-HDR from Santa Cruz Biotechnology
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Cytospin-A Double Nickase Plasmid (h) - sc-406628-NIC from Santa Cruz Biotechnology
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Cytospin-A Double Nickase Plasmid (h2) - sc-406628-NIC-2 from Santa Cruz Biotechnology
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Cytospin-A CRISPR Activation Plasmid (h) - sc-406628-ACT from Santa Cruz Biotechnology
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Cytospin-A CRISPR Activation Plasmid (h2) - sc-406628-ACT-2 from Santa Cruz Biotechnology
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Cytospin-A Lentiviral Activation Particles (h) - sc-406628-LAC from Santa Cruz Biotechnology
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Cytospin-A Lentiviral Activation Particles (h2) - sc-406628-LAC-2 from Santa Cruz Biotechnology
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Cytospin-A siRNA (h) - sc-77086 from Santa Cruz Biotechnology
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Cytospin-A shRNA Plasmid (h) - sc-77086-SH from Santa Cruz Biotechnology
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Cytospin-A shRNA (h) Lentiviral Particles - sc-77086-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU111741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20453 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20453 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11718 from Sigma-Aldrich
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SPECC1L siRNA (Human) - CRH8228 from Cohesion Biosciences
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SPECC1L - MBS8218494 from MyBioSource
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shRNA set against Human SPEC (NM_015330.3) - SHH416420 from Creative biogene
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Human SPECC1L siRNA - orb268730 from Biorbyt
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SPECC1L shRNA Plasmid (Human) - CHH8228 from Cohesion Biosciences
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SPECC1L miRNA 3'UTR clone - MiUTR4H-TG02545 from Creative biogene
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