Gene Symbol | DHX8 |
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Entrez Gene | 1659 |
Alt Symbol | DDX8, HRH1, PRP22, PRPF22 |
Species | Human |
Gene Type | protein-coding |
Description | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
Other Description | ATP-dependent RNA helicase DHX8|DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase)|DEAH box protein 8|RNA helicase HRH1 |
Swissprots | Q14562 |
Accessions | EAW51676 EAW51677 EAW51678 EAW51679 EAW51680 Q14562 AK291664 BAF84353 AK294046 BAG57398 AK303319 BAH13940 BC020697 AAH20697 BC038223 BC044586 AAH44586 BC047327 AAH47327 BE890949 D50487 BAA09078 DC310785 XM_005257113 XP_005257170 NM_001302623 NP_001289552 NM_004941 NP_004932 |
Function | Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. {ECO:0000269|PubMed:8608946}. |
Subcellular Location | Nucleus. |
Top Pathways | Spliceosome |
DDX8 CRISPR/Cas9 KO Plasmid (h) - sc-409558 from Santa Cruz Biotechnology
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DDX8 HDR Plasmid (h) - sc-409558-HDR from Santa Cruz Biotechnology
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DDX8 Double Nickase Plasmid (h) - sc-409558-NIC from Santa Cruz Biotechnology
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DDX8 Double Nickase Plasmid (h2) - sc-409558-NIC-2 from Santa Cruz Biotechnology
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DDX8 CRISPR Activation Plasmid (h) - sc-409558-ACT from Santa Cruz Biotechnology
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DDX8 CRISPR Activation Plasmid (h2) - sc-409558-ACT-2 from Santa Cruz Biotechnology
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DDX8 Lentiviral Activation Particles (h) - sc-409558-LAC from Santa Cruz Biotechnology
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DDX8 Lentiviral Activation Particles (h2) - sc-409558-LAC-2 from Santa Cruz Biotechnology
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DDX8 siRNA (h) - sc-93820 from Santa Cruz Biotechnology
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DDX8 shRNA Plasmid (h) - sc-93820-SH from Santa Cruz Biotechnology
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DDX8 shRNA (h) Lentiviral Particles - sc-93820-V from Santa Cruz Biotechnology
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DHX8 RNAi - H00001659-R02 from Novus Biologicals
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MISSION® esiRNA - EHU041941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7227 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7227 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12147 from Sigma-Aldrich
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DHX8 siRNA (Human) - CRH1170 from Cohesion Biosciences
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DHX8 - MBS8200923 from MyBioSource
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shRNA set against Human DHX8 (NM_004941.1) - SHH277981 from Creative biogene
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shRNA set against Human DHX8(NM_004941.1) - SHH004997 from Creative biogene
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Human DHX8 siRNA - orb261672 from Biorbyt
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DHX8 shRNA Plasmid (Human) - CHH1170 from Cohesion Biosciences
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DHX8 miRNA 3'UTR clone - MiUTR1H-02821 from Creative biogene
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