| Gene Symbol |
SNTB1
|
| Entrez Gene |
6641
|
| Alt Symbol |
59-DAP, A1B, BSYN2, DAPA1B, SNT2, SNT2B1, TIP-43
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
|
| Other Description |
59 kDa dystrophin-associated protein A1 basic component 1|beta-1-syntrophin|dystrophin-associated protein A1, 59kD, basic component 1|syntrophin-2|tax interaction protein 43
|
| Swissprots |
Q4KMG8 A8K9E0 O14912 Q13884
|
| Accessions |
AAA81523 EAW92008 Q13884 AF028828 AAB84253 AK025100 AK026095 AK292655 BAF85344 BC023571 BC098573 AAH98573 XM_011517239 XP_011515541 NM_021021 NP_066301
|
| Function |
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
|
| Subcellular Location |
Cell membrane, sarcolemma {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cell junction {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions. {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:8183929}.
|
![Western Blot: Syntrophin beta 1 Overexpression Lysate (Native) [NBP2-06578] - Syntrophin beta 1 Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SNTB1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4780_Syntrophin-beta-1-Overexpression-Lysate-(Native)-Western-Blot-NBP2-06578-img0002.jpg)