Gene Symbol | IL17RB |
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Entrez Gene | 55540 |
Alt Symbol | CRL4, EVI27, IL17BR, IL17RH1 |
Species | Human |
Gene Type | protein-coding |
Description | interleukin 17 receptor B |
Other Description | IL-17 receptor B|IL-17 receptor homolog 1|IL-17B receptor|IL-17RB|IL-17Rh1|cytokine receptor CRL4|cytokine receptor-like 4|interleukin 17 receptor homolog 1|interleukin 17B receptor|interleukin-17 receptor B|interleukin-17B receptor |
Swissprots | Q9NRL4 Q9BPZ0 Q9NRM5 Q9NRM6 |
Accessions | AAR89910 CAJ21520 EAW65298 EAW65299 Q9NRM6 AF208110 AAF86051 AF208111 AAF86052 AF212365 AAF78776 AF250309 AAK37428 AK307749 AY359122 AAQ89956 BC000980 AAH00980 BI458542 DA093617 DQ890929 ABM81855 DQ894090 ABM85016 XM_005265310 XP_005265367 XM_005265311 XP_005265368 XM_005265312 XP_005265369 XM_011533940 XP_011532242 XM_011533941 XP_011532243 XR_245147 XR_940467 XR_940468 NM_018725 NP_061195 NM_172234 |
Function | Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. {ECO:0000269|PubMed:11058597}. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines. |
Top Pathways | Cytokine-cytokine receptor interaction |
IL-17RB CRISPR/Cas9 KO Plasmid (h) - sc-404114 from Santa Cruz Biotechnology
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IL-17RB HDR Plasmid (h) - sc-404114-HDR from Santa Cruz Biotechnology
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IL-17RB Double Nickase Plasmid (h) - sc-404114-NIC from Santa Cruz Biotechnology
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IL-17RB Double Nickase Plasmid (h2) - sc-404114-NIC-2 from Santa Cruz Biotechnology
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IL-17RB CRISPR Activation Plasmid (h) - sc-404114-ACT from Santa Cruz Biotechnology
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IL-17RB CRISPR Activation Plasmid (h2) - sc-404114-ACT-2 from Santa Cruz Biotechnology
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IL-17RB Lentiviral Activation Particles (h) - sc-404114-LAC from Santa Cruz Biotechnology
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IL-17RB Lentiviral Activation Particles (h2) - sc-404114-LAC-2 from Santa Cruz Biotechnology
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IL-17RB siRNA (h) - sc-39964 from Santa Cruz Biotechnology
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IL-17RB shRNA Plasmid (h) - sc-39964-SH from Santa Cruz Biotechnology
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IL-17RB shRNA (h) Lentiviral Particles - sc-39964-V from Santa Cruz Biotechnology
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IL-17 RB RNAi - H00055540-R03 from Novus Biologicals
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IL-17 RB RNAi - H00055540-R04 from Novus Biologicals
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MISSION® esiRNA - EHU060131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10581 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10581 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04558 from Sigma-Aldrich
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IL17RB siRNA (Human) - CRJ0733 from Cohesion Biosciences
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IL17RB - MBS8221511 from MyBioSource
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shRNA set against Human IL17RB (NM_018725.3) - SHH318365 from Creative biogene
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shRNA set against Human IL17RB(NM_018725.3) - SHL171366 from Creative biogene
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Human IL17RB siRNA - orb271234 from Biorbyt
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IL17RB shRNA Plasmid (Human) - CHJ0733 from Cohesion Biosciences
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IL17RB miRNA 3'UTR clone - MiUTR1H-04882 from Creative biogene
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