Gene Symbol | LRRTM1 |
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Entrez Gene | 347730 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat transmembrane neuronal 1 |
Other Description | leucine-rich repeat transmembrane neuronal 1 protein|leucine-rich repeat transmembrane neuronal protein 1 |
Swissprots | D6W5K1 Q86UE6 A8K397 Q96DN1 |
Accessions | EAW99566 EAW99567 Q86UE6 AA977181 AK056644 BAB71240 AK225779 AK290512 BAF83201 AY182024 AAO67545 AY358310 AAQ88677 BC045113 AAH45113 BI756350 HQ257885 ADR82640 XR_244930 XR_939679 XR_939680 XR_939681 NM_178839 NP_849161 |
Function | Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation, acting at both pre- and postsynaptic level. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in forebrain regions including thalamus and cerebral cortex. {ECO:0000269|PubMed:12676565, ECO:0000269|PubMed:17667961}. |
LRRTM1 CRISPR/Cas9 KO Plasmid (h) - sc-408428 from Santa Cruz Biotechnology
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LRRTM1 HDR Plasmid (h) - sc-408428-HDR from Santa Cruz Biotechnology
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LRRTM1 Double Nickase Plasmid (h) - sc-408428-NIC from Santa Cruz Biotechnology
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LRRTM1 Double Nickase Plasmid (h2) - sc-408428-NIC-2 from Santa Cruz Biotechnology
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LRRTM1 CRISPR Activation Plasmid (h) - sc-408428-ACT from Santa Cruz Biotechnology
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LRRTM1 CRISPR Activation Plasmid (h2) - sc-408428-ACT-2 from Santa Cruz Biotechnology
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LRRTM1 Lentiviral Activation Particles (h) - sc-408428-LAC from Santa Cruz Biotechnology
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LRRTM1 Lentiviral Activation Particles (h2) - sc-408428-LAC-2 from Santa Cruz Biotechnology
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LRRTM1 siRNA (h) - sc-94608 from Santa Cruz Biotechnology
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LRRTM1 shRNA Plasmid (h) - sc-94608-SH from Santa Cruz Biotechnology
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LRRTM1 shRNA (h) Lentiviral Particles - sc-94608-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU155021 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12781 from Sigma-Aldrich
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LRRTM1 siRNA (Human) - CRJ7512 from Cohesion Biosciences
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shRNA set against Human LRRTM1 (NM_178839.4) - SHH335075 from Creative biogene
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shRNA set against Human LRRTM1(NM_178839.4) - SHH164405 from Creative biogene
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Human LRRTM1 siRNA - orb278013 from Biorbyt
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LRRTM1 shRNA Plasmid (Human) - CHJ7512 from Cohesion Biosciences
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LRRTM1 miRNA 3'UTR clone - MiUTR1H-05934 from Creative biogene
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