| Gene Symbol |
GAL3ST3
|
| Entrez Gene |
89792
|
| Alt Symbol |
GAL3ST-3, GAL3ST2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
galactose-3-O-sulfotransferase 3
|
| Other Description |
beta-galactose-3-O-sulfotransferase 3|gal-beta-1, 3-GalNAc 3'-sulfotransferase 3|galactose 3'-sulfotransferase|galbeta1-3GalNAc 3'-sulfotransferase 3
|
| Swissprots |
Q96A11 Q14D05
|
| Accessions |
EAW74490 Q96A11 AB053232 BAB61900 AY026481 AAK01945 BC113552 AAI13553 BC113554 AAI13555 BM673570 NM_033036 NP_149025
|
| Function |
Transfers a sulfate to position 3 of non-reducing beta- galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha- 1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha- 1,4)GlcNAc. {ECO:0000269|PubMed:11323440, ECO:0000269|PubMed:11356829}.
|
| Subcellular Location |
Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Highly expressed in thyroid, brain, kidney, heart and spinal cord. {ECO:0000269|PubMed:11323440, ECO:0000269|PubMed:11356829}.
|