Gene Symbol | ALG3 |
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Entrez Gene | 10195 |
Alt Symbol | CDG1D, CDGS4, D16Ertd36e, NOT56L, Not56 |
Species | Human |
Gene Type | protein-coding |
Description | ALG3, alpha-1,3- mannosyltransferase |
Other Description | Not56-like protein|asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)|asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase)|asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog|asparagine-linked glycosylation protein 3 homolog|carbohydrate deficient glycoprotein syndrome type IV|dol-P-Man dependent alpha(1-3)-mannosyltransferase|dol-P-Man dependent alpha-1,3- mannosyltransferase|dol-P-Man-dependent alpha(1-3)-mannosyltransferase|dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase|dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase|dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase |
Swissprots | Q9BT71 A8JZZ6 Q92685 |
Accessions | CBN61874 EAW78282 EAW78283 Q92685 AK289361 BAF82050 AK297701 BAG60059 AK299575 BAG61512 AW297350 BC002839 AAH02839 BC004313 AAH04313 BC021062 BM920198 BX339649 CX761434 DQ893160 ABM84086 DQ896456 ABM87455 KP189279 KP189280 KP189281 KP189282 KP189283 KP189284 KP189285 KP189286 KP189287 KP189288 KP189289 KP189290 KP189291 KP189292 KP189293 KP189294 KP189295 KP189296 KP189297 KP189298 KP189299 KP189300 KP189301 KP189302 KP189303 KP189304 KP189305 KP189306 KP189307 KP189308 KP189309 KP189310 KP189311 KP189312 KP189313 KP189314 KP189315 KP189316 KP189317 KP189318 KP189319 KP189320 KP189321 KP189322 KP189323 KP189324 KP189325 KP189326 KP189327 Y09022 CAA70220 XM_011512322 XP_011510624 XM_011512323 XP_011510625 NM_001006941 NP_001006942 NM_005787 NP_005778 NR_024533 NR_024534 NM_001006940 |
Function | Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol. {ECO:0000269|PubMed:10581255}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Top Pathways | N-Glycan biosynthesis |
ALG3 CRISPR/Cas9 KO Plasmid (h) - sc-411431 from Santa Cruz Biotechnology
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ALG3 HDR Plasmid (h) - sc-411431-HDR from Santa Cruz Biotechnology
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ALG3 Double Nickase Plasmid (h) - sc-411431-NIC from Santa Cruz Biotechnology
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ALG3 Double Nickase Plasmid (h2) - sc-411431-NIC-2 from Santa Cruz Biotechnology
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ALG3 CRISPR Activation Plasmid (h) - sc-411431-ACT from Santa Cruz Biotechnology
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ALG3 CRISPR Activation Plasmid (h2) - sc-411431-ACT-2 from Santa Cruz Biotechnology
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ALG3 Lentiviral Activation Particles (h) - sc-411431-LAC from Santa Cruz Biotechnology
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ALG3 Lentiviral Activation Particles (h2) - sc-411431-LAC-2 from Santa Cruz Biotechnology
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ALG3 siRNA (h) - sc-78191 from Santa Cruz Biotechnology
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ALG3 shRNA Plasmid (h) - sc-78191-SH from Santa Cruz Biotechnology
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ALG3 shRNA (h) Lentiviral Particles - sc-78191-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN3061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3061 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00301 from Sigma-Aldrich
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ALG3 siRNA (Human) - CRH6884 from Cohesion Biosciences
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ALG3 - MBS8237604 from MyBioSource
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shRNA set against Human ALG3 (NM_005787.5) - SHH235142 from Creative biogene
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Human ALG3 siRNA - orb267386 from Biorbyt
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ALG3 shRNA Plasmid (Human) - CHH6884 from Cohesion Biosciences
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ALG3 miRNA 3'UTR clone - MiUTR3H-10197 from Creative biogene
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ALG3 miRNA 3'UTR clone - MiUTR3H-10198 from Creative biogene
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