| Gene Symbol | PSMA6 |
|---|---|
| Entrez Gene | 5687 |
| Alt Symbol | IOTA, PROS27, p27K |
| Species | Human |
| Gene Type | protein-coding |
| Description | proteasome (prosome, macropain) subunit, alpha type, 6 |
| Other Description | 27 kDa prosomal protein|PROS-27|macropain iota chain|macropain subunit iota|multicatalytic endopeptidase complex iota chain|prosomal P27K protein|proteasome iota chain|proteasome subunit alpha type-6|proteasome subunit iota |
| Swissprots | B4DQR4 P60900 B4DXJ9 Q6IB60 P34062 B2R7J9 |
| Accessions | AAG61139 EAW65876 EAW65877 P60900 AA090836 AK298920 BAG61026 AK302008 BAG63411 AK313011 BAG35846 AK316223 BAH14594 BC002979 AAH02979 BC017882 AAH17882 BC022354 AAH22354 BC023659 AAH23659 BC070137 AAH70137 BG701535 BQ009843 BU198521 BU657545 CR456944 CAG33225 D28434 BAA05800 DQ892346 ABM83272 DQ895551 ABM86477 HY028439 X59417 CAA42052 X61972 CAA43964 NM_001282232 NP_001269161 NM_001282233 NP_001269162 NM_001282234 NP_001269163 NM_002791 NP_002782 NR_104110 |
| Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. |
| Subcellular Location | Cytoplasm. Nucleus. Cytoplasm, P-body {ECO:0000250}. Note=Colocalizes with TRIM5 in the cytoplasmic bodies. {ECO:0000250}. |
| Top Pathways | Proteasome |