| Gene Symbol |
DCLK1
|
| Entrez Gene |
9201
|
| Alt Symbol |
CL1, CLICK1, DCAMKL1, DCDC3A, DCLK
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
doublecortin-like kinase 1
|
| Other Description |
doublecortin domain-containing protein 3A|doublecortin-like and CAM kinase-like 1|serine/threonine-protein kinase DCLK1
|
| Swissprots |
Q5VZZ1 O15075 Q5VZZ0 Q5VZY8 B7Z3E9
|
| Accessions |
CBX55086 EAX08550 EAX08551 O15075 AB002367 BAA20824 AF052152 AF070534 AK123427 AK295102 BAH11973 AK295777 BAH12185 AK299059 BAH12940 AK299829 BAH13141 AK308925 AK311183 AK311195 AK311434 AK311438 AK311459 BC152456 AAI52457 BC160043 AAI60043 BE672499 BI824620 BM682165 BQ711413 CD619255 CR627093 XM_005266592 XP_005266649 XM_006719893 XP_006719956 NM_001195415 NP_001182344 NM_001195416 NP_001182345 NM_001195430 NP_001182359 NM_004734 NP_004725
|
| Function |
Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.
|
| Tissue Specificity |
In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain. {ECO:0000269|PubMed:10051403}.
|