Gene Symbol | CCR3 |
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Entrez Gene | 1232 |
Alt Symbol | CC-CKR-3, CD193, CKR3, CMKBR3 |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-C motif) receptor 3 |
Other Description | C-C CKR-3|C-C chemokine receptor type 3|CC chemokine receptor 3|CCR-3|b-chemokine receptor|eosinophil CC chemokine receptor 3|eosinophil eotaxin receptor |
Swissprots | Q8TDP6 Q2YDB9 Q86WD2 Q15748 P51677 F5GWL6 B3KVQ1 Q9ULY8 |
Accessions | AAB09726 AAB16831 AAL85154 AAO65970 ABK41943 BAA86964 CAD88095 CAR96700 EAW64758 EAW64759 P51677 AF026535 AAB82589 AF224495 AAK49027 AF262299 AAL85628 AF262300 AAL85629 AF262301 AAL85630 AF262302 AAL85631 AF262303 AAL85632 AF262304 BC110297 AAI10298 BC130318 AAI30319 BC130320 AAI30321 HQ258185 ADR82939 U28694 AAC50469 XM_006712960 XP_006713023 XM_011533334 XP_011531636 XM_011533335 XP_011531637 NM_001164680 NP_001158152 NM_001837 NP_001828 NM_178328 NP_847898 NM_178329 NP_847899 |
Function | Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Viral carcinogenesis |
Human CCR3 peptide - ab39734 from Abcam
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Human CCR3 peptide - ab39735 from Abcam
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CCR3 Antibody Blocking Peptide - LS-E28256 from LifeSpan Bioscience
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CCR3 Antibody Blocking Peptide - LS-E28257 from LifeSpan Bioscience
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CCR3 Antibody Blocking Peptide - LS-E28258 from LifeSpan Bioscience
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CCR3 Antibody Blocking Peptide - LS-E9791 from LifeSpan Bioscience
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CCR3 Antibody Blocking Peptide - LS-E29834 from LifeSpan Bioscience
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CCR3 Antibody Blocking Peptide - LS-E29836 from LifeSpan Bioscience
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Recombinant Human CCR3 Protein - H00001232-P01 from Novus Biologicals
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CCR3 Blocking Peptide - NBP1-76479PEP from Novus Biologicals
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CCR3 Blocking Peptide - NBP1-77065PEP from Novus Biologicals
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CCR3 Peptide - NBP1-78223PEP from Novus Biologicals
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CCR3-Antibody-Center-Blocking-Peptide - BP8806c from Abgent, a WuXi AppTec company
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CCR3 Blocking Peptide - 33R-10753 from Fitzgerald
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CD193 / CCR3 - H00001232-G01 from Acris Antibodies
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CD193 / CCR3 Control Peptide - AP30215CP-N from Acris Antibodies
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CD193 / CCR3 Control Peptide - AP30216CP-N from Acris Antibodies
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CCR3 Peptide - 1105P from ProSci
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CCR3 Peptide - 1109P from ProSci
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CCR3 fusion protein - Ag17926 from Proteintech Group
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CCR3 fusion protein - ag12933 from Proteintech Group
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Recombinant Human CCR3, GST-tagged - CCR3-10884H from Creative Biomart
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Recombinant Chemokine C-C-Motif Receptor 3 (CCR3) - RPA910Hu01 from Uscn Life Science Inc.
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ChemiSCREEN™ Membrane Preparation Recombinant Human CCR3 Chemokine Receptor - HTS008M from EMD Millipore
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Recombinant Chemokine C-C-Motif Receptor 3 (CCR3) - RPA910Hu01 from Cloud-clone
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