Gene Symbol | PDP1 |
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Entrez Gene | 54704 |
Alt Symbol | PDH, PDP, PDPC, PPM2C |
Species | Human |
Gene Type | protein-coding |
Description | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
Other Description | PDP 1|PDPC 1|[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial|protein phosphatase 2C, magnesium-dependent, catalytic subunit|pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase|pyruvate dehydrogenase phosphatase catalytic subunit 1 |
Swissprots | B3KX71 Q9P0J1 J3KPU0 Q5U5K1 |
Accessions | CAC88659 EAW91704 EAW91705 EAW91706 Q9P0J1 AF155661 AAF67480 AK022057 AK057079 BAG51859 AK126862 BAG54383 AK302651 BAG63890 AL134195 BC047619 AAH47619 BC064978 AAH64978 BC098343 AAH98343 BM973633 BQ422289 BX099681 DA240240 DA507397 DA769567 DB084539 DC369809 XM_011517135 XP_011515437 XM_011517136 XP_011515438 XM_011517137 XP_011515439 NM_001161779 NP_001155251 NM_001161780 NP_001155252 NM_001161781 NP_001155253 NM_018444 NP_060914 NM_001161778 |
Function | Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
PDPc CRISPR/Cas9 KO Plasmid (h) - sc-417451 from Santa Cruz Biotechnology
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PDPc HDR Plasmid (h) - sc-417451-HDR from Santa Cruz Biotechnology
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PDPc Double Nickase Plasmid (h) - sc-417451-NIC from Santa Cruz Biotechnology
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PDPc Double Nickase Plasmid (h2) - sc-417451-NIC-2 from Santa Cruz Biotechnology
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PDPc CRISPR Activation Plasmid (h) - sc-417451-ACT from Santa Cruz Biotechnology
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PDPc CRISPR Activation Plasmid (h2) - sc-417451-ACT-2 from Santa Cruz Biotechnology
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PDPc Lentiviral Activation Particles (h) - sc-417451-LAC from Santa Cruz Biotechnology
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PDPc Lentiviral Activation Particles (h2) - sc-417451-LAC-2 from Santa Cruz Biotechnology
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PDPc siRNA (h) - sc-77635 from Santa Cruz Biotechnology
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PDPc shRNA Plasmid (h) - sc-77635-SH from Santa Cruz Biotechnology
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PDPc shRNA (h) Lentiviral Particles - sc-77635-V from Santa Cruz Biotechnology
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Pyruvate Dehydrogenase Phosphatase/PDP1/PPM2C RNAi - H00054704-R02 from Novus Biologicals
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MISSION® esiRNA - EHU087991 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0508 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0509 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0510 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16575 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16575 from Sigma-Aldrich
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PDP1 siRNA (Human) - CRJ0179 from Cohesion Biosciences
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shRNA set against Human PDP1 (NM_018444.3) - SHH372980 from Creative biogene
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Human PDP1 siRNA - orb270680 from Biorbyt
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PDP1 shRNA Plasmid (Human) - CHJ0179 from Cohesion Biosciences
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PDP1 miRNA 3'UTR clone - MiUTR4H-TG06578 from Creative biogene
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