Gene Symbol | SLC39A7 |
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Entrez Gene | 7922 |
Alt Symbol | D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 39 (zinc transporter), member 7 |
Other Description | HLA class II region expressed gene KE4|Ke4 gene, mouse, human homolog of|histidine-rich membrane protein Ke4|really interesting new gene 5 protein|solute carrier family 39 member 7|zinc transporter SLC39A7|zrt-, Irt-like protein 7 |
Swissprots | Q9UIQ0 Q5STP8 B0UXF6 Q92504 |
Accessions | AAD12305 CAA20238 EAX03680 EAX03681 Q92504 AK225282 AK225682 AK301126 BAG62720 AK303158 BAG64260 BC000645 AAH00645 CB107807 D82060 BAA11528 DA573310 DQ891929 ABM82855 DQ895116 ABM86042 DR158641 M58660 AAA63219 NM_001077516 NP_001070984 NM_001288777 NP_001275706 NM_006979 NP_008910 |
Function | Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Transport is stimulated by growth factors, such as EGF, and Ca(2+), as well as by exogenous Zn(2+). {ECO:0000269|PubMed:14525538, ECO:0000269|PubMed:15705588, ECO:0000269|PubMed:22317921}. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:14525538, ECO:0000269|PubMed:15705588}. |
ZIP7 CRISPR/Cas9 KO Plasmid (h) - sc-409465 from Santa Cruz Biotechnology
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ZIP7 HDR Plasmid (h) - sc-409465-HDR from Santa Cruz Biotechnology
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ZIP7 Double Nickase Plasmid (h) - sc-409465-NIC from Santa Cruz Biotechnology
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ZIP7 Double Nickase Plasmid (h2) - sc-409465-NIC-2 from Santa Cruz Biotechnology
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ZIP7 CRISPR Activation Plasmid (h) - sc-409465-ACT from Santa Cruz Biotechnology
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ZIP7 CRISPR Activation Plasmid (h2) - sc-409465-ACT-2 from Santa Cruz Biotechnology
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ZIP7 Lentiviral Activation Particles (h) - sc-409465-LAC from Santa Cruz Biotechnology
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ZIP7 Lentiviral Activation Particles (h2) - sc-409465-LAC-2 from Santa Cruz Biotechnology
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ZIP7 siRNA (h) - sc-76962 from Santa Cruz Biotechnology
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ZIP7 shRNA Plasmid (h) - sc-76962-SH from Santa Cruz Biotechnology
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ZIP7 shRNA (h) Lentiviral Particles - sc-76962-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU112891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19625 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19625 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04913 from Sigma-Aldrich
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SLC39A7 siRNA (Human) - CRH5318 from Cohesion Biosciences
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SLC39A7/ZIP7 RNAi - H00007922-R01 from Novus Biologicals
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SLC39A7 - MBS8230611 from MyBioSource
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shRNA set against Human SLC39A7(NM_001077516.1) - SHL008252 from Creative biogene
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Human SLC39A7 siRNA - orb265820 from Biorbyt
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SLC39A7 shRNA Plasmid (Human) - CHH5318 from Cohesion Biosciences
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SLC39A7 miRNA 3'UTR clone - MiUTR1H-09561 from Creative biogene
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SLC39A7 miRNA 3'UTR clone - MiUTR3H-04106 from Creative biogene
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