Gene Symbol | TNFRSF4 |
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Entrez Gene | 7293 |
Alt Symbol | ACT35, CD134, IMD16, OX40, TXGP1L |
Species | Human |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 4 |
Other Description | ACT35 antigen|ATC35 antigen|CD134 antigen|OX40 antigen|OX40 cell surface antigen|OX40 homologue|OX40L receptor|TAX transcriptionally-activated glycoprotein 1 receptor|lymphoid activation antigene ACT35|tax-transcriptionally activated glycoprotein 1 receptor|tumor necrosis factor receptor superfamily member 4 |
Swissprots | Q2M312 Q13663 Q5T7M0 P43489 |
Accessions | AAZ15374 CAB96543 EAW56278 EAW56279 EAW56280 EAW56281 P43489 AW290885 AW293499 BC040257 BC105070 AAI05071 BC105072 AAI05073 S76792 AAB33944 XM_011542074 XP_011540376 XM_011542075 XP_011540377 XM_011542076 XP_011540378 XM_011542077 XP_011540379 NM_003327 NP_003318 |
Function | Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity. {ECO:0000269|PubMed:7704935}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Cytokine-cytokine receptor interaction |
Ox40 CRISPR/Cas9 KO Plasmid (h) - sc-401326 from Santa Cruz Biotechnology
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Ox40 HDR Plasmid (h) - sc-401326-HDR from Santa Cruz Biotechnology
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Ox40 Double Nickase Plasmid (h) - sc-401326-NIC from Santa Cruz Biotechnology
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Ox40 Double Nickase Plasmid (h2) - sc-401326-NIC-2 from Santa Cruz Biotechnology
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Ox40 CRISPR Activation Plasmid (h) - sc-401326-ACT from Santa Cruz Biotechnology
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Ox40 CRISPR Activation Plasmid (h2) - sc-401326-ACT-2 from Santa Cruz Biotechnology
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Ox40 Lentiviral Activation Particles (h) - sc-401326-LAC from Santa Cruz Biotechnology
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Ox40 Lentiviral Activation Particles (h2) - sc-401326-LAC-2 from Santa Cruz Biotechnology
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Ox40 siRNA (h) - sc-42822 from Santa Cruz Biotechnology
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Ox40 shRNA Plasmid (h) - sc-42822-SH from Santa Cruz Biotechnology
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Ox40 shRNA (h) Lentiviral Particles - sc-42822-V from Santa Cruz Biotechnology
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OX40/TNFRSF4 RNAi - H00007293-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21755 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21755 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00630 from Sigma-Aldrich
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TNFRSF4 siRNA (Human) - CRH4987 from Cohesion Biosciences
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TNFRSF4 - MBS8231521 from MyBioSource
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Ox40 CRISPR/Cas9 KO Plasmid (h2) - sc-401326-KO-2 from Santa Cruz Biotechnology
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Ox40 HDR Plasmid (h2) - sc-401326-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human TNFRSF4 (NM_003327.3) - SHH432048 from Creative biogene
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Human TNFRSF4 siRNA - orb265489 from Biorbyt
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TNFRSF4 shRNA Plasmid (Human) - CHH4987 from Cohesion Biosciences
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