Gene Symbol | HMGB2 |
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Entrez Gene | 3148 |
Alt Symbol | HMG2 |
Species | Human |
Gene Type | protein-coding |
Description | high mobility group box 2 |
Other Description | HMG-2|high mobility group protein 2|high mobility group protein B2|high-mobility group (nonhistone chromosomal) protein 2|high-mobility group box 2 |
Swissprots | D3DP37 P26583 B2R4K8 Q5U072 |
Accessions | AAA58659 EAX04758 EAX04759 P26583 AA576809 AK311864 BAG34805 AU129699 BC000903 BC001063 AAH01063 BC100019 AAI00020 BM727941 BM781845 BT019782 AAV38585 BT019783 AAV38586 DQ892288 ABM83214 DQ895487 ABM86413 X62534 CAA44395 Z17240 CAA78938 NM_001130688 NP_001124160 NM_001130689 NP_001124161 NM_002129 NP_002120 |
Function | DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Chromosome. |
HMG-2 CRISPR/Cas9 KO Plasmid (h) - sc-404000 from Santa Cruz Biotechnology
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HMG-2 HDR Plasmid (h) - sc-404000-HDR from Santa Cruz Biotechnology
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HMG-2 Double Nickase Plasmid (h) - sc-404000-NIC from Santa Cruz Biotechnology
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HMG-2 Double Nickase Plasmid (h2) - sc-404000-NIC-2 from Santa Cruz Biotechnology
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HMG-2 CRISPR Activation Plasmid (h) - sc-404000-ACT from Santa Cruz Biotechnology
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HMG-2 CRISPR Activation Plasmid (h2) - sc-404000-ACT-2 from Santa Cruz Biotechnology
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HMG-2 Lentiviral Activation Particles (h) - sc-404000-LAC from Santa Cruz Biotechnology
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HMG-2 Lentiviral Activation Particles (h2) - sc-404000-LAC-2 from Santa Cruz Biotechnology
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HMG-2 siRNA (h) - sc-37984 from Santa Cruz Biotechnology
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HMG-2 shRNA Plasmid (h) - sc-37984-SH from Santa Cruz Biotechnology
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HMG-2 shRNA (h) Lentiviral Particles - sc-37984-V from Santa Cruz Biotechnology
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HMGB2 RNAi - H00003148-R01 from Novus Biologicals
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MISSION® esiRNA - EHU105871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10160 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10160 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04170 from Sigma-Aldrich
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HMGB2 siRNA (Human) - CRH2148 from Cohesion Biosciences
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HMGB2 - MBS8239245 from MyBioSource
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shRNA set against Human HMGB2 (NM_002129.3) - SHH313305 from Creative biogene
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Human HMGB2 siRNA - orb262650 from Biorbyt
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HMGB2 shRNA Plasmid (Human) - CHH2148 from Cohesion Biosciences
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HMGB2 miRNA 3'UTR clone - MiUTR3H-01550 from Creative biogene
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HMGB2 miRNA 3'UTR clone - MiUTR3H-01551 from Creative biogene
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HMGB2 miRNA 3'UTR clone - MiUTR3H-01552 from Creative biogene
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